"Cracked-mud" ciprofloxacin precipitates on a corneal graft.
Journal articles
- Journal Article
Tanhehco, TY; Chiavetta, SV; Lee, PP; Fowler, AM; Afshari, NA
Published in: Ophthalmic Surg Lasers Imaging
2005
The authors describe an extreme case of ciprofloxacin deposition on the corneal graft of a 67-year-old man with a history of penetrating keratoplasty for corneal ulcer and perforation, who presented with dense, gray deposits on the anterior corneal surface after being treated with ciprofloxacin for an epithelial defect. The deposits resolved after ciprofloxacin was discontinued. The non-physiologic pH of the drug formulation is thought to trigger corneal precipitates, and it remains to be seen whether fourth-generation fluoroquinolones will have a lower incidence of ocular precipitates.
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Published In
Ophthalmic Surg Lasers Imaging
ISSN
1542-8877
Publication Date
2005
Volume
36
Issue
3
Start / End Page
252 / 253
Location
United States
Related Subject Headings
- Vision Disorders
- Recurrence
- Ophthalmology & Optometry
- Male
- Hydrogen-Ion Concentration
- Humans
- Corneal Transplantation
- Corneal Diseases
- Cornea
- Ciprofloxacin
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Tanhehco, T. Y., Chiavetta, S. V., Lee, P. P., Fowler, A. M., & Afshari, N. A. (2005). "Cracked-mud" ciprofloxacin precipitates on a corneal graft. Ophthalmic Surg Lasers Imaging, 36(3), 252–253.
Tanhehco, Tasha Y., Stephen V. Chiavetta, Paul P. Lee, Amy M. Fowler, and Natalie A. Afshari. “"Cracked-mud" ciprofloxacin precipitates on a corneal graft.” Ophthalmic Surg Lasers Imaging 36, no. 3 (2005): 252–53.
Tanhehco TY, Chiavetta SV, Lee PP, Fowler AM, Afshari NA. "Cracked-mud" ciprofloxacin precipitates on a corneal graft. Ophthalmic Surg Lasers Imaging. 2005;36(3):252–3.
Tanhehco, Tasha Y., et al. “"Cracked-mud" ciprofloxacin precipitates on a corneal graft.” Ophthalmic Surg Lasers Imaging, vol. 36, no. 3, 2005, pp. 252–53.
Tanhehco TY, Chiavetta SV, Lee PP, Fowler AM, Afshari NA. "Cracked-mud" ciprofloxacin precipitates on a corneal graft. Ophthalmic Surg Lasers Imaging. 2005;36(3):252–253.
Published In
Ophthalmic Surg Lasers Imaging
ISSN
1542-8877
Publication Date
2005
Volume
36
Issue
3
Start / End Page
252 / 253
Location
United States
Related Subject Headings
- Vision Disorders
- Recurrence
- Ophthalmology & Optometry
- Male
- Hydrogen-Ion Concentration
- Humans
- Corneal Transplantation
- Corneal Diseases
- Cornea
- Ciprofloxacin