Efficacy of intravenous immunoglobulin in Landau-Kleffner syndrome.
Publication
, Journal Article
Mikati, MA; Saab, R; Fayad, MN; Choueiri, RN
Published in: Pediatr Neurol
April 2002
We administered 2 gm/kg of intravenous gamma globulin (IVIG) to each of five consecutive patients with Landau-Kleffner syndrome, over 4 days. We compared the 1-month baseline to that following IVIG using a severity score assessing speech, comprehension, behavior, seizures, and electroencephalography. There was a significant drop in this score after IVIG (P = 0.025). Two patients had a dramatic response to IVIG, with complete resolution of symptoms. This finding suggests that IVIG has at least some efficacy for the therapy of Landau-Kleffner syndrome.
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Published In
Pediatr Neurol
DOI
ISSN
0887-8994
Publication Date
April 2002
Volume
26
Issue
4
Start / End Page
298 / 300
Location
United States
Related Subject Headings
- Statistics, Nonparametric
- Prospective Studies
- Pilot Projects
- Neurology & Neurosurgery
- Male
- Landau-Kleffner Syndrome
- Infusions, Intravenous
- Immunoglobulins, Intravenous
- Humans
- Female
Citation
APA
Chicago
ICMJE
MLA
NLM
Mikati, M. A., Saab, R., Fayad, M. N., & Choueiri, R. N. (2002). Efficacy of intravenous immunoglobulin in Landau-Kleffner syndrome. Pediatr Neurol, 26(4), 298–300. https://doi.org/10.1016/s0887-8994(01)00402-7
Mikati, Mohamad A., Raya Saab, Michel N. Fayad, and Roula N. Choueiri. “Efficacy of intravenous immunoglobulin in Landau-Kleffner syndrome.” Pediatr Neurol 26, no. 4 (April 2002): 298–300. https://doi.org/10.1016/s0887-8994(01)00402-7.
Mikati MA, Saab R, Fayad MN, Choueiri RN. Efficacy of intravenous immunoglobulin in Landau-Kleffner syndrome. Pediatr Neurol. 2002 Apr;26(4):298–300.
Mikati, Mohamad A., et al. “Efficacy of intravenous immunoglobulin in Landau-Kleffner syndrome.” Pediatr Neurol, vol. 26, no. 4, Apr. 2002, pp. 298–300. Pubmed, doi:10.1016/s0887-8994(01)00402-7.
Mikati MA, Saab R, Fayad MN, Choueiri RN. Efficacy of intravenous immunoglobulin in Landau-Kleffner syndrome. Pediatr Neurol. 2002 Apr;26(4):298–300.
Published In
Pediatr Neurol
DOI
ISSN
0887-8994
Publication Date
April 2002
Volume
26
Issue
4
Start / End Page
298 / 300
Location
United States
Related Subject Headings
- Statistics, Nonparametric
- Prospective Studies
- Pilot Projects
- Neurology & Neurosurgery
- Male
- Landau-Kleffner Syndrome
- Infusions, Intravenous
- Immunoglobulins, Intravenous
- Humans
- Female