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Calcification in pulmonary metastases.

Publication ,  Journal Article
Maile, CW; Rodan, BA; Godwin, JD; Chen, JT; Ravin, CE
Published in: Br J Radiol
February 1982

A large variety of neoplasms can produce calcified lung metastases. Three unusual examples are presented and the relevant literature is reviewed. Each case involves a neoplasm not previously reported to produce calcified lung metastases: malignant mesenchymoma, fibrosarcoma of the breast, and medullary carcinoma of the thyroid. The sarcomas are reported in the literature to develop calcified lung metastases are osteogenic sarcoma, chondrosarcoma, synovial sarcoma, and giant cell tumour. Among carcinomas, the papillary and mucinous adenocarcinomas are the histological types most likely to develop calcified lung metastases. The metastases of a number of other tumours have calcified after antineoplastic therapy. Calcification in metastases arises through a variety of mechanisms: bone formation in tumour osteoid, calcification and ossification of tumour cartilage, dystrophic calcification and ossification of tumour cartilage, dystrophic calcification and mucoid calcification. Since calcified lung metastases can strongly resemble granulomas or hamartomas, a reasonable suspicion of malignancy is necessary when evaluating calcified pulmonary nodules.

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Published In

Br J Radiol

DOI

ISSN

0007-1285

Publication Date

February 1982

Volume

55

Issue

650

Start / End Page

108 / 113

Location

England

Related Subject Headings

  • Radiography
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Mesenchymoma
  • Male
  • Lung Neoplasms
  • Humans
  • Fibrosarcoma
  • Female
  • Carcinoma
 

Citation

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Maile, C. W., Rodan, B. A., Godwin, J. D., Chen, J. T., & Ravin, C. E. (1982). Calcification in pulmonary metastases. Br J Radiol, 55(650), 108–113. https://doi.org/10.1259/0007-1285-55-650-108
Maile, C. W., B. A. Rodan, J. D. Godwin, J. T. Chen, and C. E. Ravin. “Calcification in pulmonary metastases.Br J Radiol 55, no. 650 (February 1982): 108–13. https://doi.org/10.1259/0007-1285-55-650-108.
Maile CW, Rodan BA, Godwin JD, Chen JT, Ravin CE. Calcification in pulmonary metastases. Br J Radiol. 1982 Feb;55(650):108–13.
Maile, C. W., et al. “Calcification in pulmonary metastases.Br J Radiol, vol. 55, no. 650, Feb. 1982, pp. 108–13. Pubmed, doi:10.1259/0007-1285-55-650-108.
Maile CW, Rodan BA, Godwin JD, Chen JT, Ravin CE. Calcification in pulmonary metastases. Br J Radiol. 1982 Feb;55(650):108–113.

Published In

Br J Radiol

DOI

ISSN

0007-1285

Publication Date

February 1982

Volume

55

Issue

650

Start / End Page

108 / 113

Location

England

Related Subject Headings

  • Radiography
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Mesenchymoma
  • Male
  • Lung Neoplasms
  • Humans
  • Fibrosarcoma
  • Female
  • Carcinoma