Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection.
Publication
, Journal Article
Hunter, M; Backman, V; Popescu, G; Kalashnikov, M; Boone, CW; Wax, A; Gopal, V; Badizadegan, K; Stoner, GD; Feld, MS
Published in: Physical review letters
September 2006
Light scattered from biological tissues can exhibit an inverse power law spectral component. We develop a model based on the Born approximation and von Karman (self-affine) spatial correlation of submicron tissue refractive index to account for this. The model is applied to light scattering spectra obtained from excised esophagi of normal and carcinogen-treated rats. Power law exponents used to fit dysplastic tissue site spectra are significantly smaller than those from normal sites, indicating that changes in tissue self-affinity can serve as a potential biomarker for precancer.
Duke Scholars
Published In
Physical review letters
DOI
EISSN
1079-7114
ISSN
0031-9007
Publication Date
September 2006
Volume
97
Issue
13
Start / End Page
138102
Related Subject Headings
- Scattering, Radiation
- Rats
- Neoplasms
- Models, Statistical
- Mass Screening
- Light
- Image Interpretation, Computer-Assisted
- Humans
- General Physics
- Esophagus
Citation
APA
Chicago
ICMJE
MLA
NLM
Hunter, M., Backman, V., Popescu, G., Kalashnikov, M., Boone, C. W., Wax, A., … Feld, M. S. (2006). Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection. Physical Review Letters, 97(13), 138102. https://doi.org/10.1103/physrevlett.97.138102
Hunter, Martin, Vadim Backman, Gabriel Popescu, Maxim Kalashnikov, Charles W. Boone, Adam Wax, Venkatesh Gopal, Kamran Badizadegan, Gary D. Stoner, and Michael S. Feld. “Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection.” Physical Review Letters 97, no. 13 (September 2006): 138102. https://doi.org/10.1103/physrevlett.97.138102.
Hunter M, Backman V, Popescu G, Kalashnikov M, Boone CW, Wax A, et al. Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection. Physical review letters. 2006 Sep;97(13):138102.
Hunter, Martin, et al. “Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection.” Physical Review Letters, vol. 97, no. 13, Sept. 2006, p. 138102. Epmc, doi:10.1103/physrevlett.97.138102.
Hunter M, Backman V, Popescu G, Kalashnikov M, Boone CW, Wax A, Gopal V, Badizadegan K, Stoner GD, Feld MS. Tissue self-affinity and polarized light scattering in the born approximation: a new model for precancer detection. Physical review letters. 2006 Sep;97(13):138102.
Published In
Physical review letters
DOI
EISSN
1079-7114
ISSN
0031-9007
Publication Date
September 2006
Volume
97
Issue
13
Start / End Page
138102
Related Subject Headings
- Scattering, Radiation
- Rats
- Neoplasms
- Models, Statistical
- Mass Screening
- Light
- Image Interpretation, Computer-Assisted
- Humans
- General Physics
- Esophagus