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COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus.

Publication ,  Journal Article
Metlapally, R; Li, Y-J; Tran-Viet, K-N; Abbott, D; Czaja, GR; Malecaze, F; Calvas, P; Mackey, D; Rosenberg, T; Paget, S; Zayats, T; Owen, MJ ...
Published in: Invest Ophthalmol Vis Sci
September 2009

PURPOSE: Collagen involvement in myopia development via scleral remodeling is well-known. Recently, COL1A1 and COL2A1 gene polymorphisms were reported to be associated with high-grade and common myopia, respectively. This study was conducted to investigate whether these collagen genes are associated and/or genetically linked with myopia in large Caucasian family datasets. METHODS: High-grade myopia was defined as

Duke Scholars

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

September 2009

Volume

50

Issue

9

Start / End Page

4080 / 4086

Location

United States

Related Subject Headings

  • Polymorphism, Single Nucleotide
  • Ophthalmology & Optometry
  • Myopia
  • Male
  • Humans
  • Genotype
  • Genetic Predisposition to Disease
  • Genetic Markers
  • Genetic Linkage
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Metlapally, R., Li, Y.-J., Tran-Viet, K.-N., Abbott, D., Czaja, G. R., Malecaze, F., … Young, T. L. (2009). COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus. Invest Ophthalmol Vis Sci, 50(9), 4080–4086. https://doi.org/10.1167/iovs.08-3346
Metlapally, Ravikanth, Yi-Ju Li, Khanh-Nhat Tran-Viet, Diana Abbott, Gregory R. Czaja, Francois Malecaze, Patrick Calvas, et al. “COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus.Invest Ophthalmol Vis Sci 50, no. 9 (September 2009): 4080–86. https://doi.org/10.1167/iovs.08-3346.
Metlapally R, Li Y-J, Tran-Viet K-N, Abbott D, Czaja GR, Malecaze F, et al. COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus. Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4080–6.
Metlapally, Ravikanth, et al. “COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus.Invest Ophthalmol Vis Sci, vol. 50, no. 9, Sept. 2009, pp. 4080–86. Pubmed, doi:10.1167/iovs.08-3346.
Metlapally R, Li Y-J, Tran-Viet K-N, Abbott D, Czaja GR, Malecaze F, Calvas P, Mackey D, Rosenberg T, Paget S, Zayats T, Owen MJ, Guggenheim JA, Young TL. COL1A1 and COL2A1 genes and myopia susceptibility: evidence of association and suggestive linkage to the COL2A1 locus. Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4080–4086.

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

September 2009

Volume

50

Issue

9

Start / End Page

4080 / 4086

Location

United States

Related Subject Headings

  • Polymorphism, Single Nucleotide
  • Ophthalmology & Optometry
  • Myopia
  • Male
  • Humans
  • Genotype
  • Genetic Predisposition to Disease
  • Genetic Markers
  • Genetic Linkage
  • Female