HIF-1 and tumour radiosensitivity.
Publication
, Journal Article
Moeller, BJ; Dewhirst, MW
Published in: Br J Cancer
July 3, 2006
Hypoxia-inducible factor-1 (HIF-1) plays important roles in regulating radiosensitivity, making it a potentially promising target for tumour radiosensitisation. Here, we discuss the rationale for, and the potential pitfalls of, combining HIF-1 blockade with radiotherapy. In doing so, we describe clinical scenarios in which HIF-1 inhibition might optimise tumour radiosensitivity.
Duke Scholars
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Published In
Br J Cancer
DOI
ISSN
0007-0920
Publication Date
July 3, 2006
Volume
95
Issue
1
Start / End Page
1 / 5
Location
England
Related Subject Headings
- Radiation Tolerance
- Oncology & Carcinogenesis
- Neoplasms
- Hypoxia-Inducible Factor 1
- Humans
- Gene Expression Regulation, Neoplastic
- Cell Hypoxia
- 1117 Public Health and Health Services
- 1112 Oncology and Carcinogenesis
Citation
APA
Chicago
ICMJE
MLA
NLM
Moeller, B. J., & Dewhirst, M. W. (2006). HIF-1 and tumour radiosensitivity. Br J Cancer, 95(1), 1–5. https://doi.org/10.1038/sj.bjc.6603201
Moeller, B. J., and M. W. Dewhirst. “HIF-1 and tumour radiosensitivity.” Br J Cancer 95, no. 1 (July 3, 2006): 1–5. https://doi.org/10.1038/sj.bjc.6603201.
Moeller BJ, Dewhirst MW. HIF-1 and tumour radiosensitivity. Br J Cancer. 2006 Jul 3;95(1):1–5.
Moeller, B. J., and M. W. Dewhirst. “HIF-1 and tumour radiosensitivity.” Br J Cancer, vol. 95, no. 1, July 2006, pp. 1–5. Pubmed, doi:10.1038/sj.bjc.6603201.
Moeller BJ, Dewhirst MW. HIF-1 and tumour radiosensitivity. Br J Cancer. 2006 Jul 3;95(1):1–5.
Published In
Br J Cancer
DOI
ISSN
0007-0920
Publication Date
July 3, 2006
Volume
95
Issue
1
Start / End Page
1 / 5
Location
England
Related Subject Headings
- Radiation Tolerance
- Oncology & Carcinogenesis
- Neoplasms
- Hypoxia-Inducible Factor 1
- Humans
- Gene Expression Regulation, Neoplastic
- Cell Hypoxia
- 1117 Public Health and Health Services
- 1112 Oncology and Carcinogenesis