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Pancreatic malignancy: effect of dual-phase helical CT in tumor detection and vascular opacification.

Publication ,  Journal Article
Keogan, MT; McDermott, VG; Paulson, EK; Sheafor, DH; Frederick, MG; de Long, DM; Nelson, RC
Published in: Radiology
November 1997

PURPOSE: To determine the relative value of hepatic arterial and portal venous phase helical computed tomographic (CT) scans for tumor detection and vascular opacification in patients with pancreatic malignancy. MATERIALS AND METHODS: Ninety-five patients who had or were suspected of having pancreatic disease underwent dual-phase helical CT. Arterial phase scans were acquired 20-40 seconds after contrast material administration; venous phase scans, 70-100 seconds after administration. Three readers independently scored images in a blinded fashion for the presence of tumor, for lesion attenuation relative to normal pancreas, and for vascular opacification. RESULTS: The final diagnosis was pancreatic malignancy (n = 60), acute or chronic pancreatitis (n = 22), and normal pancreas (n = 13). The readers identified possible or definite tumors on arterial phase studies in 47-50 patients and on venous phase studies in 48-53 patients (P > .10). There was no statistically significant difference in tumor attenuation between scans from the two phases (P > .05). Agreement between the readers for tumor detection was not affected by the scanning phase (P > .10). Opacification of arteries and of veins was greater on arterial phase scans and on venous phase scans, respectively (P < .001). CONCLUSION: The acquisition of arterial phase scans in addition to venous phase scans does not result in improved detection of pancreatic malignancies.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

November 1997

Volume

205

Issue

2

Start / End Page

513 / 518

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Sensitivity and Specificity
  • ROC Curve
  • Portal Vein
  • Pancreatitis
  • Pancreatic Neoplasms
  • Pancreas
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Keogan, M. T., McDermott, V. G., Paulson, E. K., Sheafor, D. H., Frederick, M. G., de Long, D. M., & Nelson, R. C. (1997). Pancreatic malignancy: effect of dual-phase helical CT in tumor detection and vascular opacification. Radiology, 205(2), 513–518. https://doi.org/10.1148/radiology.205.2.9356637
Keogan, M. T., V. G. McDermott, E. K. Paulson, D. H. Sheafor, M. G. Frederick, D. M. de Long, and R. C. Nelson. “Pancreatic malignancy: effect of dual-phase helical CT in tumor detection and vascular opacification.Radiology 205, no. 2 (November 1997): 513–18. https://doi.org/10.1148/radiology.205.2.9356637.
Keogan MT, McDermott VG, Paulson EK, Sheafor DH, Frederick MG, de Long DM, et al. Pancreatic malignancy: effect of dual-phase helical CT in tumor detection and vascular opacification. Radiology. 1997 Nov;205(2):513–8.
Keogan, M. T., et al. “Pancreatic malignancy: effect of dual-phase helical CT in tumor detection and vascular opacification.Radiology, vol. 205, no. 2, Nov. 1997, pp. 513–18. Pubmed, doi:10.1148/radiology.205.2.9356637.
Keogan MT, McDermott VG, Paulson EK, Sheafor DH, Frederick MG, de Long DM, Nelson RC. Pancreatic malignancy: effect of dual-phase helical CT in tumor detection and vascular opacification. Radiology. 1997 Nov;205(2):513–518.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

November 1997

Volume

205

Issue

2

Start / End Page

513 / 518

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Sensitivity and Specificity
  • ROC Curve
  • Portal Vein
  • Pancreatitis
  • Pancreatic Neoplasms
  • Pancreas
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male