Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.
Publication
, Journal Article
van der Walt, JM; Martin, ER; Scott, WK; Zhang, F; Nance, MA; Watts, RL; Hubble, JP; Haines, JL; Koller, WC; Lyons, K; Pahwa, R; Stern, MB ...
Published in: Neurology
April 8, 2003
Recently, the authors demonstrated linkage in idiopathic PD to a region on chromosome 8p that contains the N-acetyltransferase genes, NAT1 and NAT2. The authors examined NAT1 and NAT2 for association with PD using family-based association methods and single nucleotide polymorphisms (SNPs). The authors did not find evidence for association with increased risk for PD between any individual NAT1 or NAT2 SNP or acetylation haplotype (N = 397 families, 1,580 individuals).
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Published In
Neurology
DOI
EISSN
1526-632X
Publication Date
April 8, 2003
Volume
60
Issue
7
Start / End Page
1189 / 1191
Location
United States
Related Subject Headings
- Risk Assessment
- Polymorphism, Single Nucleotide
- Polymorphism, Genetic
- Parkinson Disease
- Neurology & Neurosurgery
- Middle Aged
- Male
- Isoenzymes
- Humans
- Haplotypes
Citation
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Chicago
ICMJE
MLA
NLM
van der Walt, J. M., Martin, E. R., Scott, W. K., Zhang, F., Nance, M. A., Watts, R. L., … Vance, J. M. (2003). Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. Neurology, 60(7), 1189–1191. https://doi.org/10.1212/01.wnl.0000055929.84668.9a
Walt, J. M. van der, E. R. Martin, W. K. Scott, F. Zhang, M. A. Nance, R. L. Watts, J. P. Hubble, et al. “Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.” Neurology 60, no. 7 (April 8, 2003): 1189–91. https://doi.org/10.1212/01.wnl.0000055929.84668.9a.
van der Walt JM, Martin ER, Scott WK, Zhang F, Nance MA, Watts RL, et al. Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. Neurology. 2003 Apr 8;60(7):1189–91.
van der Walt, J. M., et al. “Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.” Neurology, vol. 60, no. 7, Apr. 2003, pp. 1189–91. Pubmed, doi:10.1212/01.wnl.0000055929.84668.9a.
van der Walt JM, Martin ER, Scott WK, Zhang F, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Goetz CG, Small GW, Mastaglia F, Roses AD, Stajich JM, Booze MW, Fujiwara K, Gibson RA, Middleton LT, Scott BL, Pericak-Vance MA, Vance JM. Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease. Neurology. 2003 Apr 8;60(7):1189–1191.
Published In
Neurology
DOI
EISSN
1526-632X
Publication Date
April 8, 2003
Volume
60
Issue
7
Start / End Page
1189 / 1191
Location
United States
Related Subject Headings
- Risk Assessment
- Polymorphism, Single Nucleotide
- Polymorphism, Genetic
- Parkinson Disease
- Neurology & Neurosurgery
- Middle Aged
- Male
- Isoenzymes
- Humans
- Haplotypes