A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes.
Publication
, Journal Article
Lo, JY; Yu, B; Fu, HL; Bender, JE; Palmer, GM; Kuech, TF; Ramanujam, N
Published in: Opt Express
February 2, 2009
A diffuse reflectance spectroscopy system was modified as a step towards miniaturization and spectral imaging of tissue absorption and scattering. The modified system uses a tunable source and an optical fiber for illumination and a photodiode in contact with tissue for detection. Compared to the previous system, it is smaller, less costly, and has comparable performance in extracting optical properties in tissue phantoms. Wavelength reduction simulations show the feasibility of replacing the source with LEDs to further decrease system size and cost. Simulated crosstalk analysis indicates that this evolving system can be multiplexed for spectral imaging in the future.
Duke Scholars
Published In
Opt Express
DOI
EISSN
1094-4087
Publication Date
February 2, 2009
Volume
17
Issue
3
Start / End Page
1372 / 1384
Location
United States
Related Subject Headings
- Spectrum Analysis
- Scattering, Radiation
- Phantoms, Imaging
- Optics and Photonics
- Optics
- Monte Carlo Method
- Light
- Humans
- Hemoglobins
- Computer Simulation
Citation
APA
Chicago
ICMJE
MLA
NLM
Lo, J. Y., Yu, B., Fu, H. L., Bender, J. E., Palmer, G. M., Kuech, T. F., & Ramanujam, N. (2009). A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes. Opt Express, 17(3), 1372–1384. https://doi.org/10.1364/oe.17.001372
Lo, Justin Y., Bing Yu, Henry L. Fu, Janelle E. Bender, Gregory M. Palmer, Thomas F. Kuech, and Nirmala Ramanujam. “A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes.” Opt Express 17, no. 3 (February 2, 2009): 1372–84. https://doi.org/10.1364/oe.17.001372.
Lo JY, Yu B, Fu HL, Bender JE, Palmer GM, Kuech TF, et al. A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes. Opt Express. 2009 Feb 2;17(3):1372–84.
Lo, Justin Y., et al. “A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes.” Opt Express, vol. 17, no. 3, Feb. 2009, pp. 1372–84. Pubmed, doi:10.1364/oe.17.001372.
Lo JY, Yu B, Fu HL, Bender JE, Palmer GM, Kuech TF, Ramanujam N. A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes. Opt Express. 2009 Feb 2;17(3):1372–1384.
Published In
Opt Express
DOI
EISSN
1094-4087
Publication Date
February 2, 2009
Volume
17
Issue
3
Start / End Page
1372 / 1384
Location
United States
Related Subject Headings
- Spectrum Analysis
- Scattering, Radiation
- Phantoms, Imaging
- Optics and Photonics
- Optics
- Monte Carlo Method
- Light
- Humans
- Hemoglobins
- Computer Simulation