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GP IIb/IIIa blockade in elective percutaneous coronary intervention.

Publication ,  Journal Article
Dery, JP; Harrington, RA; Tcheng, JE
Published in: Curr Pharm Des
2004

Cumulative scientific evidence gathered over the past ten years has confirmed the role of platelet GP IIb/IIIa inhibitors in reducing ischemic complications of patients undergoing percutaneous coronary intervention (PCI). Recently, mortality data available on more than 20,000 patients enrolled in randomized clinical trials suggest that GP IIb/IIIa blockade also improves short and long-term survival after PCI. Despite convincing arguments, GP IIb/IIIa inhibitors are still inconsistently administered in patients undergoing coronary intervention. The following review will discuss the scientific grounds and the principal controversies surrounding the use of these compounds in patients undergoing elective percutaneous coronary intervention.

Duke Scholars

Published In

Curr Pharm Des

DOI

ISSN

1381-6128

Publication Date

2004

Volume

10

Issue

4

Start / End Page

387 / 398

Location

United Arab Emirates

Related Subject Headings

  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Platelet Aggregation Inhibitors
  • Myocardial Ischemia
  • Medicinal & Biomolecular Chemistry
  • Humans
  • Clinical Trials as Topic
  • Animals
  • Angioplasty, Balloon, Coronary
  • 3214 Pharmacology and pharmaceutical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences
 

Citation

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Dery, J. P., Harrington, R. A., & Tcheng, J. E. (2004). GP IIb/IIIa blockade in elective percutaneous coronary intervention. Curr Pharm Des, 10(4), 387–398. https://doi.org/10.2174/1381612043453306
Dery, J. P., R. A. Harrington, and J. E. Tcheng. “GP IIb/IIIa blockade in elective percutaneous coronary intervention.Curr Pharm Des 10, no. 4 (2004): 387–98. https://doi.org/10.2174/1381612043453306.
Dery JP, Harrington RA, Tcheng JE. GP IIb/IIIa blockade in elective percutaneous coronary intervention. Curr Pharm Des. 2004;10(4):387–98.
Dery, J. P., et al. “GP IIb/IIIa blockade in elective percutaneous coronary intervention.Curr Pharm Des, vol. 10, no. 4, 2004, pp. 387–98. Pubmed, doi:10.2174/1381612043453306.
Dery JP, Harrington RA, Tcheng JE. GP IIb/IIIa blockade in elective percutaneous coronary intervention. Curr Pharm Des. 2004;10(4):387–398.
Journal cover image

Published In

Curr Pharm Des

DOI

ISSN

1381-6128

Publication Date

2004

Volume

10

Issue

4

Start / End Page

387 / 398

Location

United Arab Emirates

Related Subject Headings

  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Platelet Aggregation Inhibitors
  • Myocardial Ischemia
  • Medicinal & Biomolecular Chemistry
  • Humans
  • Clinical Trials as Topic
  • Animals
  • Angioplasty, Balloon, Coronary
  • 3214 Pharmacology and pharmaceutical sciences
  • 1115 Pharmacology and Pharmaceutical Sciences