Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity.
Publication
, Journal Article
Langweiler, M; Weinhold, KJ; Matthews, TJ; Bolognesi, DP
Published in: J Natl Cancer Inst
March 1985
A 3-methylcholanthrene [(MCA) CAS: 56-49-5]-induced fibrosarcoma cell line and its Friend murine leukemia virus-infected counterpart were assessed for their susceptibility to lysis by so-called "natural" effector cells in a series of 51Cr release assays. Detailed functional and phenotypic analysis of lytic effector cell populations from normal C57BL/6 mouse spleens revealed an identity most closely associated with natural cytotoxic cells. Neither tumor cell line was found to be sensitive to natural killer-mediated lysis. Additionally, virus infection of the MCA-induced fibrosarcoma cell line did not affect susceptibility to natural cell-mediated cytotoxicity.
Duke Scholars
Published In
J Natl Cancer Inst
ISSN
0027-8874
Publication Date
March 1985
Volume
74
Issue
3
Start / End Page
699 / 704
Location
United States
Related Subject Headings
- Spleen
- Oncology & Carcinogenesis
- Neoplasms, Experimental
- Mice, Inbred C57BL
- Mice
- Methylcholanthrene
- Leukemia Virus, Murine
- Killer Cells, Natural
- Fibrosarcoma
- Female
Citation
APA
Chicago
ICMJE
MLA
NLM
Langweiler, M., Weinhold, K. J., Matthews, T. J., & Bolognesi, D. P. (1985). Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity. J Natl Cancer Inst, 74(3), 699–704.
Langweiler, M., K. J. Weinhold, T. J. Matthews, and D. P. Bolognesi. “Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity.” J Natl Cancer Inst 74, no. 3 (March 1985): 699–704.
Langweiler M, Weinhold KJ, Matthews TJ, Bolognesi DP. Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity. J Natl Cancer Inst. 1985 Mar;74(3):699–704.
Langweiler, M., et al. “Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity.” J Natl Cancer Inst, vol. 74, no. 3, Mar. 1985, pp. 699–704.
Langweiler M, Weinhold KJ, Matthews TJ, Bolognesi DP. Murine in vitro antigenic modification of tumor cells: effect on susceptibility to natural cell-mediated cytotoxicity. J Natl Cancer Inst. 1985 Mar;74(3):699–704.
Published In
J Natl Cancer Inst
ISSN
0027-8874
Publication Date
March 1985
Volume
74
Issue
3
Start / End Page
699 / 704
Location
United States
Related Subject Headings
- Spleen
- Oncology & Carcinogenesis
- Neoplasms, Experimental
- Mice, Inbred C57BL
- Mice
- Methylcholanthrene
- Leukemia Virus, Murine
- Killer Cells, Natural
- Fibrosarcoma
- Female