Frequency of celiac disease in individuals with Down syndrome in the United States.
Publication
, Journal Article
Mackey, J; Treem, WR; Worley, G; Boney, A; Hart, P; Kishnani, PS
Published in: Clin Pediatr (Phila)
May 2001
Ninety-three individuals with Down syndrome (DS) were screened to investigate the prevalence of celiac disease (CD) in the United States. Five of the 93 individuals were antiendomysial antibody (EMA) positive. Of the 5 who tested positive for EMA, 4 were biopsied, 1 refused biopsy. Three of the 4 individuals biopsied manifested changes of CD on small bowel biopsy. This gives a frequency of 3.2% of confirmed CD in our DS individuals and suggests the need for periodic screening for celiac disease in this population.
Duke Scholars
Published In
Clin Pediatr (Phila)
DOI
ISSN
0009-9228
Publication Date
May 2001
Volume
40
Issue
5
Start / End Page
249 / 252
Location
United States
Related Subject Headings
- United States
- Prospective Studies
- Prevalence
- Pediatrics
- Muscle Fibers, Skeletal
- Mass Screening
- Male
- Infant
- Immunoglobulin G
- Immunoglobulin A
Citation
APA
Chicago
ICMJE
MLA
NLM
Mackey, J., Treem, W. R., Worley, G., Boney, A., Hart, P., & Kishnani, P. S. (2001). Frequency of celiac disease in individuals with Down syndrome in the United States. Clin Pediatr (Phila), 40(5), 249–252. https://doi.org/10.1177/000992280104000502
Mackey, J., W. R. Treem, G. Worley, A. Boney, P. Hart, and P. S. Kishnani. “Frequency of celiac disease in individuals with Down syndrome in the United States.” Clin Pediatr (Phila) 40, no. 5 (May 2001): 249–52. https://doi.org/10.1177/000992280104000502.
Mackey J, Treem WR, Worley G, Boney A, Hart P, Kishnani PS. Frequency of celiac disease in individuals with Down syndrome in the United States. Clin Pediatr (Phila). 2001 May;40(5):249–52.
Mackey, J., et al. “Frequency of celiac disease in individuals with Down syndrome in the United States.” Clin Pediatr (Phila), vol. 40, no. 5, May 2001, pp. 249–52. Pubmed, doi:10.1177/000992280104000502.
Mackey J, Treem WR, Worley G, Boney A, Hart P, Kishnani PS. Frequency of celiac disease in individuals with Down syndrome in the United States. Clin Pediatr (Phila). 2001 May;40(5):249–252.
Published In
Clin Pediatr (Phila)
DOI
ISSN
0009-9228
Publication Date
May 2001
Volume
40
Issue
5
Start / End Page
249 / 252
Location
United States
Related Subject Headings
- United States
- Prospective Studies
- Prevalence
- Pediatrics
- Muscle Fibers, Skeletal
- Mass Screening
- Male
- Infant
- Immunoglobulin G
- Immunoglobulin A