Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants.
Publication
, Journal Article
Yongsunthon, R; Fowler, VG; Lower, BH; Vellano, FP; Alexander, E; Reller, LB; Corey, GR; Lower, SK
Published in: Langmuir
February 27, 2007
Atomic force microscopy was used to "fish" for binding reactions between a fibronectin-coated probe (i.e., substrate simulating an implant device) and each of 15 different isolates of Staphylococcus aureus obtained from either patients with an infected cardiac prosthesis (invasive group) or healthy human subjects (control group). There is a strong distinction (p = 0.01) in the binding-force signature observed for the invasive versus control populations. This observation suggests that a microorganism's "force taxonomy" may provide a fundamental and practical indicator of the pathogen-related risk that infections pose to patients with implanted medical devices.
Duke Scholars
Published In
Langmuir
DOI
ISSN
0743-7463
Publication Date
February 27, 2007
Volume
23
Issue
5
Start / End Page
2289 / 2292
Location
United States
Related Subject Headings
- Staphylococcus aureus
- Staphylococcal Infections
- Reproducibility of Results
- Prosthesis-Related Infections
- Prostheses and Implants
- Poisson Distribution
- Microscopy, Atomic Force
- Humans
- Fibronectins
- Chemical Physics
Citation
APA
Chicago
ICMJE
MLA
NLM
Yongsunthon, R., Fowler, V. G., Lower, B. H., Vellano, F. P., Alexander, E., Reller, L. B., … Lower, S. K. (2007). Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants. Langmuir, 23(5), 2289–2292. https://doi.org/10.1021/la063117v
Yongsunthon, Ruchirej, Vance G. Fowler, Brian H. Lower, F Paul Vellano, Emily Alexander, L Barth Reller, G Ralph Corey, and Steven K. Lower. “Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants.” Langmuir 23, no. 5 (February 27, 2007): 2289–92. https://doi.org/10.1021/la063117v.
Yongsunthon R, Fowler VG, Lower BH, Vellano FP, Alexander E, Reller LB, et al. Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants. Langmuir. 2007 Feb 27;23(5):2289–92.
Yongsunthon, Ruchirej, et al. “Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants.” Langmuir, vol. 23, no. 5, Feb. 2007, pp. 2289–92. Pubmed, doi:10.1021/la063117v.
Yongsunthon R, Fowler VG, Lower BH, Vellano FP, Alexander E, Reller LB, Corey GR, Lower SK. Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants. Langmuir. 2007 Feb 27;23(5):2289–2292.
Published In
Langmuir
DOI
ISSN
0743-7463
Publication Date
February 27, 2007
Volume
23
Issue
5
Start / End Page
2289 / 2292
Location
United States
Related Subject Headings
- Staphylococcus aureus
- Staphylococcal Infections
- Reproducibility of Results
- Prosthesis-Related Infections
- Prostheses and Implants
- Poisson Distribution
- Microscopy, Atomic Force
- Humans
- Fibronectins
- Chemical Physics