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Radiation dose-volume effects of optic nerves and chiasm.

Publication ,  Journal Article
Mayo, C; Martel, MK; Marks, LB; Flickinger, J; Nam, J; Kirkpatrick, J
Published in: Int J Radiat Oncol Biol Phys
March 1, 2010

Publications relating radiation toxicity of the optic nerves and chiasm to quantitative dose and dose-volume measures were reviewed. Few studies have adequate data for dose-volume outcome modeling. The risk of toxicity increased markedly at doses >60 Gy at approximately 1.8 Gy/fraction and at >12 Gy for single-fraction radiosurgery. The evidence is strong that radiation tolerance is increased with a reduction in the dose per fraction. Models of threshold tolerance were examined.

Duke Scholars

Published In

Int J Radiat Oncol Biol Phys

DOI

EISSN

1879-355X

Publication Date

March 1, 2010

Volume

76

Issue

3 Suppl

Start / End Page

S28 / S35

Location

United States

Related Subject Headings

  • Vision Disorders
  • Radiotherapy
  • Radiosurgery
  • Radiation Tolerance
  • Radiation Injuries
  • Radiation Dosage
  • Optic Nerve
  • Optic Chiasm
  • Oncology & Carcinogenesis
  • Models, Biological
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Mayo, C., Martel, M. K., Marks, L. B., Flickinger, J., Nam, J., & Kirkpatrick, J. (2010). Radiation dose-volume effects of optic nerves and chiasm. Int J Radiat Oncol Biol Phys, 76(3 Suppl), S28–S35. https://doi.org/10.1016/j.ijrobp.2009.07.1753
Mayo, Charles, Mary K. Martel, Lawrence B. Marks, John Flickinger, Jiho Nam, and John Kirkpatrick. “Radiation dose-volume effects of optic nerves and chiasm.Int J Radiat Oncol Biol Phys 76, no. 3 Suppl (March 1, 2010): S28–35. https://doi.org/10.1016/j.ijrobp.2009.07.1753.
Mayo C, Martel MK, Marks LB, Flickinger J, Nam J, Kirkpatrick J. Radiation dose-volume effects of optic nerves and chiasm. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S28–35.
Mayo, Charles, et al. “Radiation dose-volume effects of optic nerves and chiasm.Int J Radiat Oncol Biol Phys, vol. 76, no. 3 Suppl, Mar. 2010, pp. S28–35. Pubmed, doi:10.1016/j.ijrobp.2009.07.1753.
Mayo C, Martel MK, Marks LB, Flickinger J, Nam J, Kirkpatrick J. Radiation dose-volume effects of optic nerves and chiasm. Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S28–S35.
Journal cover image

Published In

Int J Radiat Oncol Biol Phys

DOI

EISSN

1879-355X

Publication Date

March 1, 2010

Volume

76

Issue

3 Suppl

Start / End Page

S28 / S35

Location

United States

Related Subject Headings

  • Vision Disorders
  • Radiotherapy
  • Radiosurgery
  • Radiation Tolerance
  • Radiation Injuries
  • Radiation Dosage
  • Optic Nerve
  • Optic Chiasm
  • Oncology & Carcinogenesis
  • Models, Biological