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Pulmonary alveolar proteinosis in workers at an indium processing facility.

Publication ,  Journal Article
Cummings, KJ; Donat, WE; Ettensohn, DB; Roggli, VL; Ingram, P; Kreiss, K
Published in: Am J Respir Crit Care Med
March 1, 2010

Two cases of pulmonary alveolar proteinosis, including one death, occurred in workers at a facility producing indium-tin oxide (ITO), a compound used in recent years to make flat panel displays. Both workers were exposed to airborne ITO dust and had indium in lung tissue specimens. One worker was tested for autoantibodies to granulocytemacrophage-colonystimulating factor (GM-CSF) and found to have an elevated level. These cases suggest that inhalational exposure to ITO causes pulmonary alveolar proteinosis, which may occur via an autoimmune mechanism.

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Published In

Am J Respir Crit Care Med

DOI

EISSN

1535-4970

Publication Date

March 1, 2010

Volume

181

Issue

5

Start / End Page

458 / 464

Location

United States

Related Subject Headings

  • United States
  • Tomography Scanners, X-Ray Computed
  • Tin Compounds
  • Respiratory System
  • Pulmonary Alveolar Proteinosis
  • Occupational Exposure
  • Occupational Diseases
  • Middle Aged
  • Male
  • Lung
 

Citation

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Cummings, K. J., Donat, W. E., Ettensohn, D. B., Roggli, V. L., Ingram, P., & Kreiss, K. (2010). Pulmonary alveolar proteinosis in workers at an indium processing facility. Am J Respir Crit Care Med, 181(5), 458–464. https://doi.org/10.1164/rccm.200907-1022CR
Cummings, Kristin J., Walter E. Donat, David B. Ettensohn, Victor L. Roggli, Peter Ingram, and Kathleen Kreiss. “Pulmonary alveolar proteinosis in workers at an indium processing facility.Am J Respir Crit Care Med 181, no. 5 (March 1, 2010): 458–64. https://doi.org/10.1164/rccm.200907-1022CR.
Cummings KJ, Donat WE, Ettensohn DB, Roggli VL, Ingram P, Kreiss K. Pulmonary alveolar proteinosis in workers at an indium processing facility. Am J Respir Crit Care Med. 2010 Mar 1;181(5):458–64.
Cummings, Kristin J., et al. “Pulmonary alveolar proteinosis in workers at an indium processing facility.Am J Respir Crit Care Med, vol. 181, no. 5, Mar. 2010, pp. 458–64. Pubmed, doi:10.1164/rccm.200907-1022CR.
Cummings KJ, Donat WE, Ettensohn DB, Roggli VL, Ingram P, Kreiss K. Pulmonary alveolar proteinosis in workers at an indium processing facility. Am J Respir Crit Care Med. 2010 Mar 1;181(5):458–464.

Published In

Am J Respir Crit Care Med

DOI

EISSN

1535-4970

Publication Date

March 1, 2010

Volume

181

Issue

5

Start / End Page

458 / 464

Location

United States

Related Subject Headings

  • United States
  • Tomography Scanners, X-Ray Computed
  • Tin Compounds
  • Respiratory System
  • Pulmonary Alveolar Proteinosis
  • Occupational Exposure
  • Occupational Diseases
  • Middle Aged
  • Male
  • Lung