Intensity-modulated radiation therapy for anal cancer.
Publication
, Journal Article
Czito, BG; Pepek, JM; Meyer, JJ; Yoo, S; Willett, CG
Published in: Oncology (Williston Park)
November 15, 2009
The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin. This therapy results in long-term disease-free survival and sphincter preservation in the majority of patients. Tempering these positive results is the high rate of treatment-related morbidity associated with chemoradiation therapy for anal cancer. The use of intensity-modulated radiation therapy (IMRT) has the potential to reduce acute and chronic treatment-related toxicity, minimize treatment breaks, and potentially improve disease-related outcomes by permitting radiation dose escalation in selected cases.
Duke Scholars
Published In
Oncology (Williston Park)
ISSN
0890-9091
Publication Date
November 15, 2009
Volume
23
Issue
12
Start / End Page
1082 / 1089
Location
United States
Related Subject Headings
- Randomized Controlled Trials as Topic
- Radiotherapy, Intensity-Modulated
- Mitomycin
- Humans
- Fluorouracil
- Combined Modality Therapy
- Cisplatin
- Anus Neoplasms
- Antineoplastic Combined Chemotherapy Protocols
Citation
APA
Chicago
ICMJE
MLA
NLM
Czito, B. G., Pepek, J. M., Meyer, J. J., Yoo, S., & Willett, C. G. (2009). Intensity-modulated radiation therapy for anal cancer. Oncology (Williston Park), 23(12), 1082–1089.
Czito, Brian G., Joseph M. Pepek, Jeffrey J. Meyer, Sua Yoo, and Christopher G. Willett. “Intensity-modulated radiation therapy for anal cancer.” Oncology (Williston Park) 23, no. 12 (November 15, 2009): 1082–89.
Czito BG, Pepek JM, Meyer JJ, Yoo S, Willett CG. Intensity-modulated radiation therapy for anal cancer. Oncology (Williston Park). 2009 Nov 15;23(12):1082–9.
Czito, Brian G., et al. “Intensity-modulated radiation therapy for anal cancer.” Oncology (Williston Park), vol. 23, no. 12, Nov. 2009, pp. 1082–89.
Czito BG, Pepek JM, Meyer JJ, Yoo S, Willett CG. Intensity-modulated radiation therapy for anal cancer. Oncology (Williston Park). 2009 Nov 15;23(12):1082–1089.
Published In
Oncology (Williston Park)
ISSN
0890-9091
Publication Date
November 15, 2009
Volume
23
Issue
12
Start / End Page
1082 / 1089
Location
United States
Related Subject Headings
- Randomized Controlled Trials as Topic
- Radiotherapy, Intensity-Modulated
- Mitomycin
- Humans
- Fluorouracil
- Combined Modality Therapy
- Cisplatin
- Anus Neoplasms
- Antineoplastic Combined Chemotherapy Protocols