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Treatment recommendations for primary extradural meningiomas.
Primary extradural meningiomas (PEMs) represent about 2% of all meningiomas and are often encountered by non-neurosurgeons. These lesions typically present as enlarging, painless, benign masses that can be surgically cured. Imaging is critical for defining involvement of adjacent structures; however, diagnosis depends on classic histologic patterns. Treatment for benign PEMs (WHO I) consists of resection with wide margins, whereas adjuvant therapy after resection of atypical (WHO II) or malignant (WHO III) PEMs should be considered. By using the collective experience from our comprehensive cancer center, including neuro-oncologists, neuroradiologists, and neurosurgeons, in addition to a complete literature review, the authors have established treatment guidelines not previously reported. This manuscript describes key features of these challenging tumors to aid in diagnosis, presents the largest published review of all reported PEMs (n = 163), and provides salient treatment guidelines to surgeons unfamiliar with these challenging tumors.
Duke Scholars
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Related Subject Headings
- Practice Guidelines as Topic
- Oncology & Carcinogenesis
- Meningioma
- Meningeal Neoplasms
- Humans
- Head and Neck Neoplasms
- Bone Neoplasms
- Algorithms
- Abdominal Neoplasms
- 4206 Public health
Citation
![Journal cover image](https://secure.syndetics.com/index.aspx?isbn=/lc.gif&issn=0008-543X&client=dukeuniv)
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Practice Guidelines as Topic
- Oncology & Carcinogenesis
- Meningioma
- Meningeal Neoplasms
- Humans
- Head and Neck Neoplasms
- Bone Neoplasms
- Algorithms
- Abdominal Neoplasms
- 4206 Public health