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Retrospective analysis of the use of cyclosporine in myasthenia gravis.

Publication ,  Journal Article
Ciafaloni, E; Nikhar, NK; Massey, JM; Sanders, DB
Published in: Neurology
August 8, 2000

The authors reviewed the records of patients with myasthenia gravis who took cyclosporine for at least 6 months between November 1987 and January 1999. Of 57 patients who took cyclosporine for an average of 3.5 years, 55 (96%) had clinical improvement. The median time to best clinical response was 7 months. Corticosteroids were discontinued or decreased in 95% of 38 patients taking them. Major side effects included elevated serum creatinine (28%) and malignancy (11%). Five percent could not afford or tolerate the drug.

Duke Scholars

Published In

Neurology

DOI

ISSN

0028-3878

Publication Date

August 8, 2000

Volume

55

Issue

3

Start / End Page

448 / 450

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Neurology & Neurosurgery
  • Myasthenia Gravis
  • Middle Aged
  • Male
  • Immunosuppressive Agents
  • Humans
  • Female
  • Cyclosporine
  • Aged, 80 and over
 

Citation

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Ciafaloni, E., Nikhar, N. K., Massey, J. M., & Sanders, D. B. (2000). Retrospective analysis of the use of cyclosporine in myasthenia gravis. Neurology, 55(3), 448–450. https://doi.org/10.1212/wnl.55.3.448
Ciafaloni, E., N. K. Nikhar, J. M. Massey, and D. B. Sanders. “Retrospective analysis of the use of cyclosporine in myasthenia gravis.Neurology 55, no. 3 (August 8, 2000): 448–50. https://doi.org/10.1212/wnl.55.3.448.
Ciafaloni E, Nikhar NK, Massey JM, Sanders DB. Retrospective analysis of the use of cyclosporine in myasthenia gravis. Neurology. 2000 Aug 8;55(3):448–50.
Ciafaloni, E., et al. “Retrospective analysis of the use of cyclosporine in myasthenia gravis.Neurology, vol. 55, no. 3, Aug. 2000, pp. 448–50. Pubmed, doi:10.1212/wnl.55.3.448.
Ciafaloni E, Nikhar NK, Massey JM, Sanders DB. Retrospective analysis of the use of cyclosporine in myasthenia gravis. Neurology. 2000 Aug 8;55(3):448–450.

Published In

Neurology

DOI

ISSN

0028-3878

Publication Date

August 8, 2000

Volume

55

Issue

3

Start / End Page

448 / 450

Location

United States

Related Subject Headings

  • Retrospective Studies
  • Neurology & Neurosurgery
  • Myasthenia Gravis
  • Middle Aged
  • Male
  • Immunosuppressive Agents
  • Humans
  • Female
  • Cyclosporine
  • Aged, 80 and over