Clinical aspects of MuSK antibody positive seronegative MG.
Publication
, Journal Article
Sanders, DB; El-Salem, K; Massey, JM; McConville, J; Vincent, A
Published in: Neurology
June 24, 2003
Serum antibodies to muscle-specific receptor tyrosine kinase were detected in 12 of 32 patients with generalized seronegative MG. All were women, with onset between ages 21 and 59 years. Seven had prominent neck, shoulder, or respiratory muscle weakness and little or delayed ocular muscle involvement. The response to cholinesterase inhibitors was variable, and electromyographic findings suggested myopathy in several. None improved after thymectomy. All patients improved after plasma exchange, and most had a good response to selected immunotherapy. MuSK antibody status should help diagnose MG with atypical presentations and ensure appropriate patient treatment.
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Published In
Neurology
DOI
EISSN
1526-632X
Publication Date
June 24, 2003
Volume
60
Issue
12
Start / End Page
1978 / 1980
Location
United States
Related Subject Headings
- Treatment Outcome
- Thymectomy
- Single-Blind Method
- Receptors, Cholinergic
- Receptor Protein-Tyrosine Kinases
- Plasma Exchange
- Organ Specificity
- Neurology & Neurosurgery
- Neural Conduction
- Myasthenia Gravis
Citation
APA
Chicago
ICMJE
MLA
NLM
Sanders, D. B., El-Salem, K., Massey, J. M., McConville, J., & Vincent, A. (2003). Clinical aspects of MuSK antibody positive seronegative MG. Neurology, 60(12), 1978–1980. https://doi.org/10.1212/01.wnl.0000065882.63904.53
Sanders, D. B., K. El-Salem, J. M. Massey, J. McConville, and A. Vincent. “Clinical aspects of MuSK antibody positive seronegative MG.” Neurology 60, no. 12 (June 24, 2003): 1978–80. https://doi.org/10.1212/01.wnl.0000065882.63904.53.
Sanders DB, El-Salem K, Massey JM, McConville J, Vincent A. Clinical aspects of MuSK antibody positive seronegative MG. Neurology. 2003 Jun 24;60(12):1978–80.
Sanders, D. B., et al. “Clinical aspects of MuSK antibody positive seronegative MG.” Neurology, vol. 60, no. 12, June 2003, pp. 1978–80. Pubmed, doi:10.1212/01.wnl.0000065882.63904.53.
Sanders DB, El-Salem K, Massey JM, McConville J, Vincent A. Clinical aspects of MuSK antibody positive seronegative MG. Neurology. 2003 Jun 24;60(12):1978–1980.
Published In
Neurology
DOI
EISSN
1526-632X
Publication Date
June 24, 2003
Volume
60
Issue
12
Start / End Page
1978 / 1980
Location
United States
Related Subject Headings
- Treatment Outcome
- Thymectomy
- Single-Blind Method
- Receptors, Cholinergic
- Receptor Protein-Tyrosine Kinases
- Plasma Exchange
- Organ Specificity
- Neurology & Neurosurgery
- Neural Conduction
- Myasthenia Gravis