Skip to main content
Journal cover image

Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments.

Publication ,  Journal Article
Brady, SL; Brown, WE; Clift, CG; Yoo, S; Oldham, M
Published in: Phys Med Biol
April 21, 2010

This work presents an investigation into the use of PRESAGE dosimeters with an optical-CT scanner as a 3D dosimetry system for quantitative verification of respiratory-gated treatments. The CIRS dynamic thorax phantom was modified to incorporate a moving PRESAGE dosimeter-simulating respiration motion in the lungs. A simple AP/PA lung treatment plan was delivered three times to the phantom containing a different but geometrically identical PRESAGE insert each time. Each delivery represented a treatment scenario: static, motion (free-breathing) and gated. The dose distributions, in the three dosimeters, were digitized by the optical-CT scanner. Improved optical-CT readout yielded an increased signal-to-noise ratio by a factor of 3 and decreased reconstruction artifacts compared with prior work. Independent measurements of dose distributions were obtained in the central plane using EBT film. Dose distributions were normalized to a point corresponding to the 100% isodose region prior to the measurement of dose profiles and gamma maps. These measurements were used to quantify the agreement between measured and ECLIPSE(R) dose distributions. Average gamma pass rates between PRESAGE and EBT were >99% (criteria 3% dose difference and 1.2 mm distance-to-agreement) for all three treatments. Gamma pass rates between PRESAGE and ECLIPSE(R) 3D dose distributions showed excellent agreement for the gated treatment (100% pass rate), but poor for the motion scenario (85% pass rate). This work demonstrates the feasibility of using PRESAGE/optical-CT 3D dosimetry to verify gating-enabled radiation treatments. The capability of the Varian gating system to compensate for motion in this treatment scenario was demonstrated.

Duke Scholars

Published In

Phys Med Biol

DOI

EISSN

1361-6560

Publication Date

April 21, 2010

Volume

55

Issue

8

Start / End Page

2187 / 2201

Location

England

Related Subject Headings

  • Tomography, X-Ray Computed
  • Time Factors
  • Respiration
  • Reference Standards
  • Radiometry
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Movement
  • Humans
  • Feasibility Studies
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Brady, S. L., Brown, W. E., Clift, C. G., Yoo, S., & Oldham, M. (2010). Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments. Phys Med Biol, 55(8), 2187–2201. https://doi.org/10.1088/0031-9155/55/8/005
Brady, Samuel L., William E. Brown, Corey G. Clift, Sua Yoo, and Mark Oldham. “Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments.Phys Med Biol 55, no. 8 (April 21, 2010): 2187–2201. https://doi.org/10.1088/0031-9155/55/8/005.
Brady SL, Brown WE, Clift CG, Yoo S, Oldham M. Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments. Phys Med Biol. 2010 Apr 21;55(8):2187–201.
Brady, Samuel L., et al. “Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments.Phys Med Biol, vol. 55, no. 8, Apr. 2010, pp. 2187–201. Pubmed, doi:10.1088/0031-9155/55/8/005.
Brady SL, Brown WE, Clift CG, Yoo S, Oldham M. Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments. Phys Med Biol. 2010 Apr 21;55(8):2187–2201.
Journal cover image

Published In

Phys Med Biol

DOI

EISSN

1361-6560

Publication Date

April 21, 2010

Volume

55

Issue

8

Start / End Page

2187 / 2201

Location

England

Related Subject Headings

  • Tomography, X-Ray Computed
  • Time Factors
  • Respiration
  • Reference Standards
  • Radiometry
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Movement
  • Humans
  • Feasibility Studies