A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer.
Publication
, Journal Article
Tang, P; Wang, J; Hicks, DG; Wang, X; Schiffhauer, L; McMahon, L; Yang, Q; Shayne, M; Huston, A; Skinner, KA; Griggs, J; Lyman, G
Published in: Cancer Invest
November 2010
Among the 77 infiltrating breast carcinomas, we found that progesterone receptor (PR) expression was inversely associated with recurrence score (RS, p < .0001). RS is also significantly associated with tubule formation, mitosis, and luminal B subtype. The equation of RS = 17.489 + 2.071 (tubal formation) + 2.926 (mitosis) -2.408 (PR) -1.061 (HER2) + 7.051 (luminal A) + 29.172 (luminal B) predicts RS with an R² of 0.65. In conclusion, PR negativity, luminal B subtype, tubal formation, and mitosis are strongly correlated with a higher RS.
Duke Scholars
Published In
Cancer Invest
DOI
EISSN
1532-4192
Publication Date
November 2010
Volume
28
Issue
9
Start / End Page
978 / 982
Location
England
Related Subject Headings
- Retrospective Studies
- Receptors, Progesterone
- Receptors, Estrogen
- Receptor, erbB-2
- Receptor, ErbB-2
- Prognosis
- Oncology & Carcinogenesis
- Neoplasm Recurrence, Local
- Middle Aged
- Immunohistochemistry
Citation
APA
Chicago
ICMJE
MLA
NLM
Tang, P., Wang, J., Hicks, D. G., Wang, X., Schiffhauer, L., McMahon, L., … Lyman, G. (2010). A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer. Cancer Invest, 28(9), 978–982. https://doi.org/10.3109/07357907.2010.496754
Tang, Ping, Jianmin Wang, David G. Hicks, Xi Wang, Linda Schiffhauer, Loralee McMahon, Qi Yang, et al. “A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer.” Cancer Invest 28, no. 9 (November 2010): 978–82. https://doi.org/10.3109/07357907.2010.496754.
Tang P, Wang J, Hicks DG, Wang X, Schiffhauer L, McMahon L, et al. A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer. Cancer Invest. 2010 Nov;28(9):978–82.
Tang, Ping, et al. “A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer.” Cancer Invest, vol. 28, no. 9, Nov. 2010, pp. 978–82. Pubmed, doi:10.3109/07357907.2010.496754.
Tang P, Wang J, Hicks DG, Wang X, Schiffhauer L, McMahon L, Yang Q, Shayne M, Huston A, Skinner KA, Griggs J, Lyman G. A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer. Cancer Invest. 2010 Nov;28(9):978–982.
Published In
Cancer Invest
DOI
EISSN
1532-4192
Publication Date
November 2010
Volume
28
Issue
9
Start / End Page
978 / 982
Location
England
Related Subject Headings
- Retrospective Studies
- Receptors, Progesterone
- Receptors, Estrogen
- Receptor, erbB-2
- Receptor, ErbB-2
- Prognosis
- Oncology & Carcinogenesis
- Neoplasm Recurrence, Local
- Middle Aged
- Immunohistochemistry