Autoantibodies and their idiotypes.
Publication
, Journal Article
Pisetsky, DS
Published in: Current opinion in rheumatology
October 1992
Antinuclear antibodies occur prominently in systemic lupus erythematosus and serve as markers of underlying pathogenetic disturbances. Although these antibodies display features indicative of genetic control and in vivo selection by self-antigen, other mechanisms shaping the B-cell repertoire may influence their production. Provocative new animal models provide systems for analyzing the cellular and genetic disturbances promoting these responses, as well as the role of pathogenic specificities in inducing tissue injury.
Duke Scholars
Published In
Current opinion in rheumatology
EISSN
1531-6963
ISSN
1040-8711
Publication Date
October 1992
Volume
4
Issue
5
Start / End Page
635 / 643
Related Subject Headings
- Mice
- Lupus Erythematosus, Systemic
- Immunoglobulin Idiotypes
- Humans
- Genes, Immunoglobulin
- Autoantibodies
- Arthritis & Rheumatology
- Antibody Specificity
- Antibodies, Antinuclear
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Pisetsky, D. S. (1992). Autoantibodies and their idiotypes. Current Opinion in Rheumatology, 4(5), 635–643.
Pisetsky, D. S. “Autoantibodies and their idiotypes.” Current Opinion in Rheumatology 4, no. 5 (October 1992): 635–43.
Pisetsky DS. Autoantibodies and their idiotypes. Current opinion in rheumatology. 1992 Oct;4(5):635–43.
Pisetsky, D. S. “Autoantibodies and their idiotypes.” Current Opinion in Rheumatology, vol. 4, no. 5, Oct. 1992, pp. 635–43.
Pisetsky DS. Autoantibodies and their idiotypes. Current opinion in rheumatology. 1992 Oct;4(5):635–643.
Published In
Current opinion in rheumatology
EISSN
1531-6963
ISSN
1040-8711
Publication Date
October 1992
Volume
4
Issue
5
Start / End Page
635 / 643
Related Subject Headings
- Mice
- Lupus Erythematosus, Systemic
- Immunoglobulin Idiotypes
- Humans
- Genes, Immunoglobulin
- Autoantibodies
- Arthritis & Rheumatology
- Antibody Specificity
- Antibodies, Antinuclear
- Animals