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Autoantibodies and their idiotypes.

Publication ,  Journal Article
Pisetsky, DS
Published in: Curr Opin Rheumatol
October 1992

Antinuclear antibodies occur prominently in systemic lupus erythematosus and serve as markers of underlying pathogenetic disturbances. Although these antibodies display features indicative of genetic control and in vivo selection by self-antigen, other mechanisms shaping the B-cell repertoire may influence their production. Provocative new animal models provide systems for analyzing the cellular and genetic disturbances promoting these responses, as well as the role of pathogenic specificities in inducing tissue injury.

Duke Scholars

Published In

Curr Opin Rheumatol

ISSN

1040-8711

Publication Date

October 1992

Volume

4

Issue

5

Start / End Page

635 / 643

Location

United States

Related Subject Headings

  • Mice
  • Lupus Erythematosus, Systemic
  • Immunoglobulin Idiotypes
  • Humans
  • Genes, Immunoglobulin
  • Autoantibodies
  • Arthritis & Rheumatology
  • Antibody Specificity
  • Antibodies, Antinuclear
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Pisetsky, D. S. (1992). Autoantibodies and their idiotypes. Curr Opin Rheumatol, 4(5), 635–643.
Pisetsky, D. S. “Autoantibodies and their idiotypes.Curr Opin Rheumatol 4, no. 5 (October 1992): 635–43.
Pisetsky DS. Autoantibodies and their idiotypes. Curr Opin Rheumatol. 1992 Oct;4(5):635–43.
Pisetsky, D. S. “Autoantibodies and their idiotypes.Curr Opin Rheumatol, vol. 4, no. 5, Oct. 1992, pp. 635–43.
Pisetsky DS. Autoantibodies and their idiotypes. Curr Opin Rheumatol. 1992 Oct;4(5):635–643.

Published In

Curr Opin Rheumatol

ISSN

1040-8711

Publication Date

October 1992

Volume

4

Issue

5

Start / End Page

635 / 643

Location

United States

Related Subject Headings

  • Mice
  • Lupus Erythematosus, Systemic
  • Immunoglobulin Idiotypes
  • Humans
  • Genes, Immunoglobulin
  • Autoantibodies
  • Arthritis & Rheumatology
  • Antibody Specificity
  • Antibodies, Antinuclear
  • Animals