Early rapid rise in intraocular pressure after intravitreal triamcinolone acetonide injection.

PURPOSE: To report the occurrences of early rapid increases in intraocular (IOP) after intravitreal glucocorticoid injection. DESIGN: Observational case series. METHODS: We retrospectively reviewed the records of three patients seen and treated at Duke Eye Center. RESULTS: In all three cases, a significant rise in IOP occurred within 1 week of intravitreal triamcinolone injection for refractory macular edema. In one patient, a white material was found in the angle on gonioscopy. All three cases required surgical intervention to reduce the IOP. CONCLUSIONS: Considering the early rapid rise in IOP in these three cases, we suggest that clinicians closely monitor patients after intravitreal triamcinolone injections for the development of acute glaucoma. Additionally, it may be advisable to perform gonioscopic examinations to look for any abnormal accumulation of material in the angle.

Duke Scholars

Author Pratap Challa Ophthalmology, Glaucoma

Author Leon Walker Herndon Jr. Ophthalmology, Glaucoma

Author Paul Pue-Jung Lee Ophthalmology, Glaucoma