Overview
As a physician-scientist investigator, Dr. Challa has a special research interest in the genetic basis of inherited eye diseases. He has active projects investigating the genetics of Pseudoexfoliation associated glaucoma and the cellular basis for glaucoma development. He also studies ocular drug delivery and is involved in developing long-term delivery devices for glaucoma medications. He also investigates novel compounds that may eventually be used for treating glaucoma. In addition to basic science research, he also has clinical research interests including evaluating the effectiveness of new glaucoma therapies.
Current Duke Appointments & Affiliations
Professor of Ophthalmology
·
2022 - Present
Ophthalmology, Glaucoma,
Ophthalmology
Residency Director in the Department of Ophthalmology
·
2001 - Present
Ophthalmology,
Clinical Science Departments
Recent Scholarly Works
Contemporary diversity trends among matched ophthalmology residents in the USA.
Journal article BMJ Lead · June 26, 2026 BACKGROUND: Ophthalmology remains one of the least diverse medical specialties, despite ongoing efforts to promote inclusion. To address the gap in recent literature and understand the demographic trajectory of this specialty, this study analyses current d ... Full text Link to item CitePrimary Open-Angle Glaucoma Preferred Practice PatternĀ®
Journal article Ophthalmology · April 1, 2026 Full text CitePrimary Angle-Closure Disease Preferred Practice PatternĀ®.
Journal article Ophthalmology · April 2026 Full text Link to item CiteRecent Grants
Role of Glypicans in Aqueous Humor Outflow, IOP and Glaucoma
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2028Assessment of topical ocular drug candidate
ResearchPrincipal Investigator · Awarded by Alcon Research · 2025 - 2027Animal models of Glaucoma and Eye Disease (FY27)
ResearchPrincipal Investigator · Awarded by Alcon Research · 2026 - 2027View All Grants
Education
University of Florida ·
1993
M.D.