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Pratap Challa
Professor of Ophthalmology
Ophthalmology, Glaucoma
chall001@mc.duke.edu
Box 3802 Med Ctr, Durham, NC 27710
Wadsworth Bldg, Durham, NC 27710
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AT A GLANCE
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Credentials
Education
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Academic Experience
Current Appointments & Affiliations
Previous Appointments & Affiliations
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Expertise
Global Scholarship
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Research
Selected Grants
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Publications
Selected Publications
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Artistic Works / Events
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Teaching
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Advising & Mentoring
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Recognition
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Professional Activities
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Selected Grants
Role of Glypicans in Aqueous Humor Outflow, IOP and Glaucoma
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2024 - 2028
Assessment of intravitreal implant degradation over time
Research
Principal Investigator ·
Awarded by Alcon Research ·
2024 - 2026
Role of Septin Cytoskeleton in Trabecular Meshwork, IOP and Glaucoma
Research
Co-Principal Investigator ·
Awarded by BrightFocus Foundation ·
2023 - 2025
Animal models of Glaucoma and Eye Disease
Research
Principal Investigator ·
Awarded by Aerie Pharmaceuticals, Inc. ·
2022 - 2025
Ocular Tissue Distribution, Efficacy, and Tolerability Study of Small-Molecule Inhibitors in a Rabbit Models of Allergic Eye Disease
Research
Principal Investigator ·
Awarded by Perfuse Therapeutics ·
2022 - 2025
More
Role of Glypicans in Aqueous Humor Outflow, IOP and Glaucoma
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2024 - 2028
Assessment of intravitreal implant degradation over time
Research
Principal Investigator ·
Awarded by Alcon Research ·
2024 - 2026
Role of Septin Cytoskeleton in Trabecular Meshwork, IOP and Glaucoma
Research
Co-Principal Investigator ·
Awarded by BrightFocus Foundation ·
2023 - 2025
Animal models of Glaucoma and Eye Disease
Research
Principal Investigator ·
Awarded by Aerie Pharmaceuticals, Inc. ·
2022 - 2025
Ocular Tissue Distribution, Efficacy, and Tolerability Study of Small-Molecule Inhibitors in a Rabbit Models of Allergic Eye Disease
Research
Principal Investigator ·
Awarded by Perfuse Therapeutics ·
2022 - 2025
The Swine model of VEGF-induced vascular leakage and interventions thereof
Research
Principal Investigator ·
Awarded by Aerie Pharmaceuticals, Inc. ·
2022 - 2024
The Role of GDF-15 in Aqueous Humor Outflow and Glaucoma
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2018 - 2024
Trabecular Meshwork Cytoskeletal Signaling-Regulation of Aqueous Humor Outflow
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2008 - 2024
Lysosomal Enzymes in Outflow Pathway Physiology and Pathophysiology
Research
Collaborator ·
Awarded by National Institutes of Health ·
2017 - 2022
Novel Experimental Model for Pseudoexfolliation Syndrome
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2018 - 2020
Optimization of a Cell Culture Model for Pseudoexfoliation Syndrome
Research
Collaborator ·
Awarded by The Glaucoma Foundation ·
2018 - 2019
MicroRNA-directed modulation of intraocular pressure
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2013 - 2018
Mechanisms in Exfoliation Glaucoma: Effect of Genetic Risk Variants and Ocular Cell Stressors on LOXL1 Expression
Research
Consultant ·
Awarded by The Glaucoma Foundation ·
2015 - 2016
Exosomal RNAs and Aqueous Humor Dynamics in Exfoliation Glaucoma
Research
Co Investigator ·
Awarded by Glaucoma Research Foundation ·
2014 - 2014
Cellular Senescence and Glaucoma
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2011 - 2013
The Molecular Basis of Pseudoexfoliation Syndrome
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2003 - 2009
Genetic Studies of POAG in Ghana, West Africa
Research
Investigator ·
Awarded by National Institutes of Health ·
2003 - 2007
Healthy Vision 2010 Community Awards Program
Public Service
Principal Investigator ·
Awarded by National Institutes of Health ·
2004 - 2004
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