Skip to main content
Journal cover image

Computer-aided detection (CAD) of lung nodules in CT scans: radiologist performance and reading time with incremental CAD assistance.

Publication ,  Journal Article
Roos, JE; Paik, D; Olsen, D; Liu, EG; Chow, LC; Leung, AN; Mindelzun, R; Choudhury, KR; Naidich, DP; Napel, S; Rubin, GD
Published in: Eur Radiol
March 2010

OBJECTIVE: The diagnostic performance of radiologists using incremental CAD assistance for lung nodule detection on CT and their temporal variation in performance during CAD evaluation was assessed. METHODS: CAD was applied to 20 chest multidetector-row computed tomography (MDCT) scans containing 190 non-calcified > or =3-mm nodules. After free search, three radiologists independently evaluated a maximum of up to 50 CAD detections/patient. Multiple free-response ROC curves were generated for free search and successive CAD evaluation, by incrementally adding CAD detections one at a time to the radiologists' performance. RESULTS: The sensitivity for free search was 53% (range, 44%-59%) at 1.15 false positives (FP)/patient and increased with CAD to 69% (range, 59-82%) at 1.45 FP/patient. CAD evaluation initially resulted in a sharp rise in sensitivity of 14% with a minimal increase in FP over a time period of 100 s, followed by flattening of the sensitivity increase to only 2%. This transition resulted from a greater prevalence of true positive (TP) versus FP detections at early CAD evaluation and not by a temporal change in readers' performance. The time spent for TP (9.5 s +/- 4.5 s) and false negative (FN) (8.4 s +/- 6.7 s) detections was similar; FP decisions took two- to three-times longer (14.4 s +/- 8.7 s) than true negative (TN) decisions (4.7 s +/- 1.3 s). CONCLUSIONS: When CAD output is ordered by CAD score, an initial period of rapid performance improvement slows significantly over time because of non-uniformity in the distribution of TP CAD output and not to a changing reader performance over time.

Duke Scholars

Published In

Eur Radiol

DOI

EISSN

1432-1084

Publication Date

March 2010

Volume

20

Issue

3

Start / End Page

549 / 557

Location

Germany

Related Subject Headings

  • Young Adult
  • Workload
  • Tomography, X-Ray Computed
  • Task Performance and Analysis
  • Solitary Pulmonary Nodule
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiographic Image Enhancement
  • Professional Competence
  • Physicians
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Roos, J. E., Paik, D., Olsen, D., Liu, E. G., Chow, L. C., Leung, A. N., … Rubin, G. D. (2010). Computer-aided detection (CAD) of lung nodules in CT scans: radiologist performance and reading time with incremental CAD assistance. Eur Radiol, 20(3), 549–557. https://doi.org/10.1007/s00330-009-1596-y
Journal cover image

Published In

Eur Radiol

DOI

EISSN

1432-1084

Publication Date

March 2010

Volume

20

Issue

3

Start / End Page

549 / 557

Location

Germany

Related Subject Headings

  • Young Adult
  • Workload
  • Tomography, X-Ray Computed
  • Task Performance and Analysis
  • Solitary Pulmonary Nodule
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiographic Image Enhancement
  • Professional Competence
  • Physicians