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Corticosteroid therapy and chronic obstructive pulmonary disease.

Publication ,  Journal Article
MacIntyre, NR
Published in: Respir Care
March 2006

Chronic obstructive pulmonary disease is characterized in part by a chronic inflammatory state in the airways (largely from chronic noxious stimuli such as tobacco smoke), punctuated with acute inflammatory exacerbations, which are often infectious. Although pathologically and biochemically different from the inflammation of asthma, the chronic inflammation of chronic obstructive pulmonary disease, especially in subgroups with asthma-like features and especially during exacerbations, might be expected to respond to corticosteroid therapy, as does asthma. Complications from long-term corticosteroid use are important, but they appear less when the corticosteroid is given via the inhaled route. Clinical evidence is particularly strong supporting the use of inhaled corticosteroids to prevent exacerbations and oral corticosteroids to reduce the duration and impact of exacerbations.

Duke Scholars

Published In

Respir Care

ISSN

0020-1324

Publication Date

March 2006

Volume

51

Issue

3

Start / End Page

289 / 296

Location

United States

Related Subject Headings

  • United States
  • Risk Factors
  • Respiratory System
  • Pulmonary Disease, Chronic Obstructive
  • Humans
  • Evidence-Based Medicine
  • Adrenal Cortex Hormones
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
MacIntyre, N. R. (2006). Corticosteroid therapy and chronic obstructive pulmonary disease. Respir Care, 51(3), 289–296.
MacIntyre, Neil R. “Corticosteroid therapy and chronic obstructive pulmonary disease.Respir Care 51, no. 3 (March 2006): 289–96.
MacIntyre NR. Corticosteroid therapy and chronic obstructive pulmonary disease. Respir Care. 2006 Mar;51(3):289–96.
MacIntyre, Neil R. “Corticosteroid therapy and chronic obstructive pulmonary disease.Respir Care, vol. 51, no. 3, Mar. 2006, pp. 289–96.
MacIntyre NR. Corticosteroid therapy and chronic obstructive pulmonary disease. Respir Care. 2006 Mar;51(3):289–296.

Published In

Respir Care

ISSN

0020-1324

Publication Date

March 2006

Volume

51

Issue

3

Start / End Page

289 / 296

Location

United States

Related Subject Headings

  • United States
  • Risk Factors
  • Respiratory System
  • Pulmonary Disease, Chronic Obstructive
  • Humans
  • Evidence-Based Medicine
  • Adrenal Cortex Hormones
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences