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Aerosol delivery through an artificial airway.

Publication ,  Journal Article
MacIntyre, NR
Published in: Respir Care
November 2002

For both lung and systemic diseases, aerosol delivery of drugs into the lungs can often offer substantial advantages over other routes of administration. In the intensive care unit, however, the artificial airway can be a substantial barrier to aerosol delivery, so clinicians must pay careful attention to the ventilator pattern, the delivery gas humidity/density, the device characteristics, and the circuit/tube properties. When those are optimized, aerosol delivery from a nebulizer or metered-dose inhaler and through an endotracheal tube can begin to approach that seen in a nonintubated patient. Novel approaches, such as generating the aerosol within the airway, offer the opportunity to greatly increase deposition efficiency and focal drug targeting in intubated patients.

Duke Scholars

Published In

Respir Care

ISSN

0020-1324

Publication Date

November 2002

Volume

47

Issue

11

Start / End Page

1279 / 1288

Location

United States

Related Subject Headings

  • Respiratory System
  • Nebulizers and Vaporizers
  • Metered Dose Inhalers
  • Intubation, Intratracheal
  • Humans
  • Equipment Design
  • Drug Delivery Systems
  • Aerosols
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
 

Citation

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MLA
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MacIntyre, N. R. (2002). Aerosol delivery through an artificial airway. Respir Care, 47(11), 1279–1288.
MacIntyre, Neil R. “Aerosol delivery through an artificial airway.Respir Care 47, no. 11 (November 2002): 1279–88.
MacIntyre NR. Aerosol delivery through an artificial airway. Respir Care. 2002 Nov;47(11):1279–88.
MacIntyre, Neil R. “Aerosol delivery through an artificial airway.Respir Care, vol. 47, no. 11, Nov. 2002, pp. 1279–88.
MacIntyre NR. Aerosol delivery through an artificial airway. Respir Care. 2002 Nov;47(11):1279–1288.

Published In

Respir Care

ISSN

0020-1324

Publication Date

November 2002

Volume

47

Issue

11

Start / End Page

1279 / 1288

Location

United States

Related Subject Headings

  • Respiratory System
  • Nebulizers and Vaporizers
  • Metered Dose Inhalers
  • Intubation, Intratracheal
  • Humans
  • Equipment Design
  • Drug Delivery Systems
  • Aerosols
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology