
Pathogenic mechanisms of vessel damage in vasculitis syndromes.
Publication
, Journal Article
Sundy, JS; Haynes, BF
Published in: Rheum Dis Clin North Am
November 1995
The pathogenesis of vasculitis syndromes is via a diverse array of mechanisms that disrupt vessel integrity and produce clinical signs and symptoms of tissue ischemia. In many patients with vasculitis, it is not possible to directly classify the syndrome according to a particular schema, and attempts to define the pathogenic process mediating vessel damage by biopsy and laboratory tests may be useful to guide therapy. The continued use of new techniques to probe immune cell types and cytokines in vasculitis lesional tissues will further clarify molecular mechanisms of vascular damage, and it is hoped that they will lead to new and more effective therapeutic strategies targeted at the vasculitis syndromes.
Duke Scholars
Published In
Rheum Dis Clin North Am
ISSN
0889-857X
Publication Date
November 1995
Volume
21
Issue
4
Start / End Page
861 / 881
Location
United States
Related Subject Headings
- Vasculitis
- Neoplasms
- Lysosomes
- Infections
- Immunity, Cellular
- Humans
- Granuloma
- Blood Vessels
- Arthritis & Rheumatology
- Antibody Formation
Citation
APA
Chicago
ICMJE
MLA
NLM
Sundy, J. S., & Haynes, B. F. (1995). Pathogenic mechanisms of vessel damage in vasculitis syndromes. Rheum Dis Clin North Am, 21(4), 861–881.
Sundy, J. S., and B. F. Haynes. “Pathogenic mechanisms of vessel damage in vasculitis syndromes.” Rheum Dis Clin North Am 21, no. 4 (November 1995): 861–81.
Sundy JS, Haynes BF. Pathogenic mechanisms of vessel damage in vasculitis syndromes. Rheum Dis Clin North Am. 1995 Nov;21(4):861–81.
Sundy, J. S., and B. F. Haynes. “Pathogenic mechanisms of vessel damage in vasculitis syndromes.” Rheum Dis Clin North Am, vol. 21, no. 4, Nov. 1995, pp. 861–81.
Sundy JS, Haynes BF. Pathogenic mechanisms of vessel damage in vasculitis syndromes. Rheum Dis Clin North Am. 1995 Nov;21(4):861–881.

Published In
Rheum Dis Clin North Am
ISSN
0889-857X
Publication Date
November 1995
Volume
21
Issue
4
Start / End Page
861 / 881
Location
United States
Related Subject Headings
- Vasculitis
- Neoplasms
- Lysosomes
- Infections
- Immunity, Cellular
- Humans
- Granuloma
- Blood Vessels
- Arthritis & Rheumatology
- Antibody Formation