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Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group.

Publication ,  Journal Article
Haynes, BF; Reisner, EG; Hemler, ME; Strominger, JL; Eisenbarth, GS
Published in: Hum Immunol
July 1982
Published version (DOI) Link to item

The selection and characterization of a cloned murine monoclonal antibody (4D12) that defines an HLA allotypic determinant is described. Antibody 4D12 immunoprecipitates HLA heavy and light chains. From studies on 4D12 reactivity with a large panel of well-characterized target cells, antibody 4D12 defines a public HLA determinant that includes specificities within but not identical to the B5 cross-reacting group. Antibody 4D12 should be useful in the study of HLA-B5--related supratypic antigens.

Duke Scholars

Barton Ford Haynes
Author Barton Ford Haynes Medicine, Duke Human Vaccine Institute

Published In

Hum Immunol

DOI

10.1016/0198-8859(82)90001-5

ISSN

0198-8859

Publication Date

July 1982

Volume

4

Issue

4

Start / End Page

273 / 285

Location

United States

Related Subject Headings

  • Thymus Gland
  • T-Lymphocytes
  • Mice, Inbred BALB C
  • Mice
  • Immunology
  • Immunoglobulin Allotypes
  • Hybridomas
  • Humans
  • Histocompatibility Testing
  • HLA-B Antigens
 

Citation

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ICMJE
MLA
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Haynes, B. F., Reisner, E. G., Hemler, M. E., Strominger, J. L., & Eisenbarth, G. S. (1982). Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group. Hum Immunol, 4(4), 273–285. https://doi.org/10.1016/0198-8859(82)90001-5
Haynes, B. F., E. G. Reisner, M. E. Hemler, J. L. Strominger, and G. S. Eisenbarth. “Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group.” Hum Immunol 4, no. 4 (July 1982): 273–85. https://doi.org/10.1016/0198-8859(82)90001-5.
Haynes BF, Reisner EG, Hemler ME, Strominger JL, Eisenbarth GS. Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group. Hum Immunol. 1982 Jul;4(4):273–85.
Haynes, B. F., et al. “Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group.” Hum Immunol, vol. 4, no. 4, July 1982, pp. 273–85. Pubmed, doi:10.1016/0198-8859(82)90001-5.
Haynes BF, Reisner EG, Hemler ME, Strominger JL, Eisenbarth GS. Description of monoclonal antibody defining an HLA allotypic determinant that includes specificities within the B5 cross-reacting group. Hum Immunol. 1982 Jul;4(4):273–285.
Journal cover image

Published In

Hum Immunol

DOI

10.1016/0198-8859(82)90001-5

ISSN

0198-8859

Publication Date

July 1982

Volume

4

Issue

4

Start / End Page

273 / 285

Location

United States

Related Subject Headings

  • Thymus Gland
  • T-Lymphocytes
  • Mice, Inbred BALB C
  • Mice
  • Immunology
  • Immunoglobulin Allotypes
  • Hybridomas
  • Humans
  • Histocompatibility Testing
  • HLA-B Antigens