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Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.

Publication ,  Journal Article
Allen, TM; Jing, P; Calore, B; Horton, H; O'Connor, DH; Hanke, T; Piekarczyk, M; Ruddersdorf, R; Mothé, BR; Emerson, C; Wilson, N; Lifson, JD ...
Published in: J Virol
October 2002

Vaccine-induced cytotoxic T lymphocytes (CTL) have been implicated in the control of virus replication in simian immunodeficiency virus (SIV)-challenged and simian-human immunodeficiency virus-challenged macaques. Therefore, we wanted to test the impact that vaccine-induced CTL responses against an immunodominant Gag epitope might have in the absence of other immune responses. By themselves, these strong CTL responses failed to control SIVmac239 replication.

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Published In

J Virol

DOI

ISSN

0022-538X

Publication Date

October 2002

Volume

76

Issue

20

Start / End Page

10507 / 10511

Location

United States

Related Subject Headings

  • Virology
  • Vaccination
  • T-Lymphocytes, Cytotoxic
  • Simian immunodeficiency virus
  • Simian Immunodeficiency Virus
  • Macaca mulatta
  • Immunodominant Epitopes
  • Humans
  • Histocompatibility Antigens Class I
  • Gene Products, gag
 

Citation

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ICMJE
MLA
NLM
Allen, T. M., Jing, P., Calore, B., Horton, H., O’Connor, D. H., Hanke, T., … Watkins, D. I. (2002). Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. J Virol, 76(20), 10507–10511. https://doi.org/10.1128/jvi.76.20.10507-10511.2002
Allen, Todd M., Peicheng Jing, Briana Calore, Helen Horton, David H. O’Connor, Tomas Hanke, Marian Piekarczyk, et al. “Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.J Virol 76, no. 20 (October 2002): 10507–11. https://doi.org/10.1128/jvi.76.20.10507-10511.2002.
Allen TM, Jing P, Calore B, Horton H, O’Connor DH, Hanke T, et al. Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. J Virol. 2002 Oct;76(20):10507–11.
Allen, Todd M., et al. “Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection.J Virol, vol. 76, no. 20, Oct. 2002, pp. 10507–11. Pubmed, doi:10.1128/jvi.76.20.10507-10511.2002.
Allen TM, Jing P, Calore B, Horton H, O’Connor DH, Hanke T, Piekarczyk M, Ruddersdorf R, Mothé BR, Emerson C, Wilson N, Lifson JD, Belyakov IM, Berzofsky JA, Wang C, Allison DB, Montefiori DC, Desrosiers RC, Wolinsky S, Kunstman KJ, Altman JD, Sette A, McMichael AJ, Watkins DI. Effects of cytotoxic T lymphocytes (CTL) directed against a single simian immunodeficiency virus (SIV) Gag CTL epitope on the course of SIVmac239 infection. J Virol. 2002 Oct;76(20):10507–10511.

Published In

J Virol

DOI

ISSN

0022-538X

Publication Date

October 2002

Volume

76

Issue

20

Start / End Page

10507 / 10511

Location

United States

Related Subject Headings

  • Virology
  • Vaccination
  • T-Lymphocytes, Cytotoxic
  • Simian immunodeficiency virus
  • Simian Immunodeficiency Virus
  • Macaca mulatta
  • Immunodominant Epitopes
  • Humans
  • Histocompatibility Antigens Class I
  • Gene Products, gag