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Microrheology, stress fluctuations, and active behavior of living cells.

Publication ,  Journal Article
Lau, AWC; Hoffman, BD; Davies, A; Crocker, JC; Lubensky, TC
Published in: Physical review letters
November 2003

We report the first measurements of the intrinsic strain fluctuations of living cells using a recently developed tracer correlation technique along with a theoretical framework for interpreting such data in heterogeneous media with nonthermal driving. The fluctuations' spatial and temporal correlations indicate that the cytoskeleton can be treated as a course-grained continuum with power-law rheology, driven by a spatially random stress tensor field. Combined with recent cell rheology results, our data imply that intracellular stress fluctuations have a nearly 1/omega2 power spectrum, as expected for a continuum with a slowly evolving internal prestress.

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Published In

Physical review letters

DOI

EISSN

1079-7114

ISSN

0031-9007

Publication Date

November 2003

Volume

91

Issue

19

Start / End Page

198101

Related Subject Headings

  • Viscosity
  • Stress, Mechanical
  • Rheology
  • Mathematical Computing
  • General Physics
  • Elasticity
  • Cell Physiological Phenomena
  • 51 Physical sciences
  • 49 Mathematical sciences
  • 40 Engineering
 

Citation

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ICMJE
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Lau, A. W. C., Hoffman, B. D., Davies, A., Crocker, J. C., & Lubensky, T. C. (2003). Microrheology, stress fluctuations, and active behavior of living cells. Physical Review Letters, 91(19), 198101. https://doi.org/10.1103/physrevlett.91.198101
Lau, A. W. C., B. D. Hoffman, A. Davies, J. C. Crocker, and T. C. Lubensky. “Microrheology, stress fluctuations, and active behavior of living cells.Physical Review Letters 91, no. 19 (November 2003): 198101. https://doi.org/10.1103/physrevlett.91.198101.
Lau AWC, Hoffman BD, Davies A, Crocker JC, Lubensky TC. Microrheology, stress fluctuations, and active behavior of living cells. Physical review letters. 2003 Nov;91(19):198101.
Lau, A. W. C., et al. “Microrheology, stress fluctuations, and active behavior of living cells.Physical Review Letters, vol. 91, no. 19, Nov. 2003, p. 198101. Epmc, doi:10.1103/physrevlett.91.198101.
Lau AWC, Hoffman BD, Davies A, Crocker JC, Lubensky TC. Microrheology, stress fluctuations, and active behavior of living cells. Physical review letters. 2003 Nov;91(19):198101.

Published In

Physical review letters

DOI

EISSN

1079-7114

ISSN

0031-9007

Publication Date

November 2003

Volume

91

Issue

19

Start / End Page

198101

Related Subject Headings

  • Viscosity
  • Stress, Mechanical
  • Rheology
  • Mathematical Computing
  • General Physics
  • Elasticity
  • Cell Physiological Phenomena
  • 51 Physical sciences
  • 49 Mathematical sciences
  • 40 Engineering