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Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis.

Publication ,  Journal Article
Kontoyiannis, DP; Lewis, RE; Alexander, BD; Lortholary, O; Dromer, F; Gupta, KL; John, GT; Del Busto, R; Klintmalm, GB; Somani, J; Lyon, GM ...
Published in: Antimicrob Agents Chemother
February 2008

Synergistic interactions were observed between CIs and antifungal agents against 53 (90%) of 59 Cryptococcus neoformans isolates from solid organ transplant recipients with cryptococcosis and may account for better outcomes in patients with cryptococcosis receiving these immunosuppressive agents.

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Published In

Antimicrob Agents Chemother

DOI

ISSN

0066-4804

Publication Date

February 2008

Volume

52

Issue

2

Start / End Page

735 / 738

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Tacrolimus
  • Organ Transplantation
  • Microbiology
  • Microbial Sensitivity Tests
  • Immunosuppressive Agents
  • Humans
  • Drug Synergism
  • Cryptococcus neoformans
  • Cryptococcosis
 

Citation

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Kontoyiannis, D. P., Lewis, R. E., Alexander, B. D., Lortholary, O., Dromer, F., Gupta, K. L., … Singh, N. (2008). Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis. Antimicrob Agents Chemother, 52(2), 735–738. https://doi.org/10.1128/AAC.00990-07
Kontoyiannis, Dimitrios P., Russell E. Lewis, Barbara D. Alexander, Olivier Lortholary, Françoise Dromer, Krishan L. Gupta, George T. John, et al. “Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis.Antimicrob Agents Chemother 52, no. 2 (February 2008): 735–38. https://doi.org/10.1128/AAC.00990-07.
Kontoyiannis, Dimitrios P., et al. “Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis.Antimicrob Agents Chemother, vol. 52, no. 2, Feb. 2008, pp. 735–38. Pubmed, doi:10.1128/AAC.00990-07.
Kontoyiannis DP, Lewis RE, Alexander BD, Lortholary O, Dromer F, Gupta KL, John GT, Del Busto R, Klintmalm GB, Somani J, Lyon GM, Pursell K, Stosor V, Munoz P, Limaye AP, Kalil AC, Pruett TL, Garcia-Diaz J, Humar A, Houston S, House AA, Wray D, Orloff S, Dowdy LA, Fisher RA, Heitman J, Albert ND, Wagener MM, Singh N. Calcineurin inhibitor agents interact synergistically with antifungal agents in vitro against Cryptococcus neoformans isolates: correlation with outcome in solid organ transplant recipients with cryptococcosis. Antimicrob Agents Chemother. 2008 Feb;52(2):735–738.

Published In

Antimicrob Agents Chemother

DOI

ISSN

0066-4804

Publication Date

February 2008

Volume

52

Issue

2

Start / End Page

735 / 738

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Tacrolimus
  • Organ Transplantation
  • Microbiology
  • Microbial Sensitivity Tests
  • Immunosuppressive Agents
  • Humans
  • Drug Synergism
  • Cryptococcus neoformans
  • Cryptococcosis