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Direct-acting antiviral medications for chronic hepatitis C virus infection.

Publication ,  Journal Article
Jazwinski, AB; Muir, AJ
Published in: Gastroenterol Hepatol (N Y)
March 2011

Treatment of hepatitis C virus has traditionally been difficult because of low rates of treatment success and high rates of treatment discontinuation due to side effects. Current standard therapy consists of pegylated interferon α and ribavirin, both of which have nonspecific and largely unknown mechanisms of action. New therapies are in development that act directly on the hepatitis C virus at various points in the viral life cycle. Published clinical trial data on these therapies are summarized in this paper. A new era of hepatitis C virus treatment is beginning, the ultimate goals of which will be directly targeting the virus, shortening the length of therapy, improving sustained virologic response rates, and minimizing side effects.

Duke Scholars

Published In

Gastroenterol Hepatol (N Y)

ISSN

1554-7914

Publication Date

March 2011

Volume

7

Issue

3

Start / End Page

154 / 162

Location

United States

Related Subject Headings

  • Gastroenterology & Hepatology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Jazwinski, A. B., & Muir, A. J. (2011). Direct-acting antiviral medications for chronic hepatitis C virus infection. Gastroenterol Hepatol (N Y), 7(3), 154–162.
Jazwinski, Alison B., and Andrew J. Muir. “Direct-acting antiviral medications for chronic hepatitis C virus infection.Gastroenterol Hepatol (N Y) 7, no. 3 (March 2011): 154–62.
Jazwinski AB, Muir AJ. Direct-acting antiviral medications for chronic hepatitis C virus infection. Gastroenterol Hepatol (N Y). 2011 Mar;7(3):154–62.
Jazwinski, Alison B., and Andrew J. Muir. “Direct-acting antiviral medications for chronic hepatitis C virus infection.Gastroenterol Hepatol (N Y), vol. 7, no. 3, Mar. 2011, pp. 154–62.
Jazwinski AB, Muir AJ. Direct-acting antiviral medications for chronic hepatitis C virus infection. Gastroenterol Hepatol (N Y). 2011 Mar;7(3):154–162.

Published In

Gastroenterol Hepatol (N Y)

ISSN

1554-7914

Publication Date

March 2011

Volume

7

Issue

3

Start / End Page

154 / 162

Location

United States

Related Subject Headings

  • Gastroenterology & Hepatology