Drosophila melanogaster as a model system for genetics of postnatal cardiac function.
Publication
, Journal Article
Wolf, MJ; Rockman, HA
Published in: Drug Discov Today Dis Models
October 1, 2008
The fruit fly, Drosophila melanogaster, is an excellent model system that has a vast set of molecular tools and mutants to dissect the genetic pathways that are responsible for the normal and abnormal cardiac function. While the majority of studies have focused on heart development in the Drosophila embryo, attention has recently focused on the structure and function of the adult fly heart as a model of human heart failure. Here we review strategies to identify novel genes and pathways that cause or modify dilated cardiomyopathy in adult Drosophila.
Duke Scholars
Published In
Drug Discov Today Dis Models
DOI
ISSN
1740-6757
Publication Date
October 1, 2008
Volume
5
Issue
3
Start / End Page
117 / 123
Location
Netherlands
Related Subject Headings
- Neurology & Neurosurgery
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences
- 1109 Neurosciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Wolf, M. J., & Rockman, H. A. (2008). Drosophila melanogaster as a model system for genetics of postnatal cardiac function. Drug Discov Today Dis Models, 5(3), 117–123. https://doi.org/10.1016/j.ddmod.2009.02.002
Wolf, Matthew J., and Howard A. Rockman. “Drosophila melanogaster as a model system for genetics of postnatal cardiac function.” Drug Discov Today Dis Models 5, no. 3 (October 1, 2008): 117–23. https://doi.org/10.1016/j.ddmod.2009.02.002.
Wolf MJ, Rockman HA. Drosophila melanogaster as a model system for genetics of postnatal cardiac function. Drug Discov Today Dis Models. 2008 Oct 1;5(3):117–23.
Wolf, Matthew J., and Howard A. Rockman. “Drosophila melanogaster as a model system for genetics of postnatal cardiac function.” Drug Discov Today Dis Models, vol. 5, no. 3, Oct. 2008, pp. 117–23. Pubmed, doi:10.1016/j.ddmod.2009.02.002.
Wolf MJ, Rockman HA. Drosophila melanogaster as a model system for genetics of postnatal cardiac function. Drug Discov Today Dis Models. 2008 Oct 1;5(3):117–123.
Published In
Drug Discov Today Dis Models
DOI
ISSN
1740-6757
Publication Date
October 1, 2008
Volume
5
Issue
3
Start / End Page
117 / 123
Location
Netherlands
Related Subject Headings
- Neurology & Neurosurgery
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences
- 1109 Neurosciences