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Relationship of global assessment of change to AUSCAN and pinch and grip strength among individuals with hand osteoarthritis.

Publication ,  Journal Article
Allen, KD; Jordan, JM; Renner, JB; Kraus, VB
Published in: Osteoarthritis Cartilage
December 2006

OBJECTIVE: This study assessed the utility and construct validity of a new patient global assessment of symptom change for hand osteoarthritis (OA) by examining its associations with change over time in grip strength, pinch strength, and AUStralian CANadian Osteoarthritis Hand Index (AUSCAN). METHODS: Participants (N=531, 80% female, mean age=68) were part of a study on the Genetics of Generalized Osteoarthritis (GOGO) and completed two assessments (average 4 years apart). At the second assessment, participants described change in their right and left hand pain, aching, and stiffness on a 15-point scale with descriptors ranging from "Great deal worse" to "Great deal better". Linear regression models examined associations of global change scores with changes in hand strength and AUSCAN, controlling for age, gender, number of hand joints with OA, and time between assessments. RESULTS: Both right and left hand global assessment of change scores were significantly associated with change in AUSCAN, grip strength, and right hand pinch strength (P<0.05), and approached significance for left hand pinch strength (P=0.06). The strongest associations were between global change scores and AUSCAN change (right hand: beta=0.29, P<0.001; left hand: beta=0.27, P<0.001). Associations of change scores with grip and pinch strength were stronger among participants with greater radiographic OA severity at baseline. CONCLUSION: Results support the validity of this new global assessment of symptom change. This measure is particularly useful for assessing change over time when no baseline data are available. Additional research should examine this measure's responsiveness in the context of clinical trials.

Duke Scholars

Published In

Osteoarthritis Cartilage

DOI

ISSN

1063-4584

Publication Date

December 2006

Volume

14

Issue

12

Start / End Page

1281 / 1287

Location

England

Related Subject Headings

  • Severity of Illness Index
  • Reproducibility of Results
  • Osteoarthritis
  • Muscle Strength
  • Middle Aged
  • Male
  • Humans
  • Hand Strength
  • Hand Joints
  • Follow-Up Studies
 

Citation

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ICMJE
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Allen, K. D., Jordan, J. M., Renner, J. B., & Kraus, V. B. (2006). Relationship of global assessment of change to AUSCAN and pinch and grip strength among individuals with hand osteoarthritis. Osteoarthritis Cartilage, 14(12), 1281–1287. https://doi.org/10.1016/j.joca.2006.06.004
Allen, K. D., J. M. Jordan, J. B. Renner, and V. B. Kraus. “Relationship of global assessment of change to AUSCAN and pinch and grip strength among individuals with hand osteoarthritis.Osteoarthritis Cartilage 14, no. 12 (December 2006): 1281–87. https://doi.org/10.1016/j.joca.2006.06.004.
Allen KD, Jordan JM, Renner JB, Kraus VB. Relationship of global assessment of change to AUSCAN and pinch and grip strength among individuals with hand osteoarthritis. Osteoarthritis Cartilage. 2006 Dec;14(12):1281–7.
Allen, K. D., et al. “Relationship of global assessment of change to AUSCAN and pinch and grip strength among individuals with hand osteoarthritis.Osteoarthritis Cartilage, vol. 14, no. 12, Dec. 2006, pp. 1281–87. Pubmed, doi:10.1016/j.joca.2006.06.004.
Allen KD, Jordan JM, Renner JB, Kraus VB. Relationship of global assessment of change to AUSCAN and pinch and grip strength among individuals with hand osteoarthritis. Osteoarthritis Cartilage. 2006 Dec;14(12):1281–1287.
Journal cover image

Published In

Osteoarthritis Cartilage

DOI

ISSN

1063-4584

Publication Date

December 2006

Volume

14

Issue

12

Start / End Page

1281 / 1287

Location

England

Related Subject Headings

  • Severity of Illness Index
  • Reproducibility of Results
  • Osteoarthritis
  • Muscle Strength
  • Middle Aged
  • Male
  • Humans
  • Hand Strength
  • Hand Joints
  • Follow-Up Studies