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Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro-CT.

Publication ,  Journal Article
Song, J; Liu, QH; Johnson, GA; Badea, CT
Published in: Med Phys
November 2007

Recent advances in murine cardiac studies with three-dimensional (3D) cone beam micro-CT used a retrospective gating technique. However, this sampling technique results in a limited number of projections with an irregular angular distribution due to the temporal resolution requirements and radiation dose restrictions. Both angular irregularity and undersampling complicate the reconstruction process, since they cause significant streaking artifacts. This work provides an iterative reconstruction solution to address this particular challenge. A sparseness prior regularized weighted l2 norm optimization is proposed to mitigate streaking artifacts based on the fact that most medical images are compressible. Total variation is implemented in this work as the regularizer for its simplicity. Comparison studies are conducted on a 3D cardiac mouse phantom generated with experimental data. After optimization, the method is applied to in vivo cardiac micro-CT data.

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Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

November 2007

Volume

34

Issue

11

Start / End Page

4476 / 4483

Location

United States

Related Subject Headings

  • X-Rays
  • Tomography, X-Ray Computed
  • Time Factors
  • Scattering, Radiation
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Myocardium
  • Models, Statistical
  • Mice, Inbred C57BL
  • Mice
 

Citation

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Song, J., Liu, Q. H., Johnson, G. A., & Badea, C. T. (2007). Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro-CT. Med Phys, 34(11), 4476–4483. https://doi.org/10.1118/1.2795830
Song, Jiayu, Qing H. Liu, G Allan Johnson, and Cristian T. Badea. “Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro-CT.Med Phys 34, no. 11 (November 2007): 4476–83. https://doi.org/10.1118/1.2795830.
Song J, Liu QH, Johnson GA, Badea CT. Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro-CT. Med Phys. 2007 Nov;34(11):4476–83.
Song, Jiayu, et al. “Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro-CT.Med Phys, vol. 34, no. 11, Nov. 2007, pp. 4476–83. Pubmed, doi:10.1118/1.2795830.
Song J, Liu QH, Johnson GA, Badea CT. Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro-CT. Med Phys. 2007 Nov;34(11):4476–4483.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

November 2007

Volume

34

Issue

11

Start / End Page

4476 / 4483

Location

United States

Related Subject Headings

  • X-Rays
  • Tomography, X-Ray Computed
  • Time Factors
  • Scattering, Radiation
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Myocardium
  • Models, Statistical
  • Mice, Inbred C57BL
  • Mice