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Biology and functions of the RGS9 isoforms.

Publication ,  Chapter
Martemyanov, KA; Arshavsky, VY
2009

Two splice isoforms of the ninth member of the regulator of G protein signaling (RGS) protein family are expressed in the nervous system, where they are engaged in such diverse functions as vision and behavior. RGS9-1 regulates phototransduction in rods and cones, while RGS9-2 regulates dopamine and opioid signaling in the basal ganglia. The main goal of this review is to illustrate how these functions are fulfilled through the interplay between the intrinsic molecular properties of RGS9 isoforms and their interactions with several key protein partners in the cells in which they are expressed.

Duke Scholars

DOI

Publication Date

2009

Volume

86

Start / End Page

205 / 227

Related Subject Headings

  • RGS Proteins
  • Protein Structure, Tertiary
  • Protein Isoforms
  • Protein Binding
  • Photoreceptor Cells, Vertebrate
  • Light Signal Transduction
  • Humans
  • Animals
 

Citation

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ICMJE
MLA
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Martemyanov, K. A., & Arshavsky, V. Y. (2009). Biology and functions of the RGS9 isoforms. (Vol. 86, pp. 205–227). https://doi.org/10.1016/S1877-1173(09)86007-9
Martemyanov, Kirill A., and Vadim Y. Arshavsky. “Biology and functions of the RGS9 isoforms.,” 86:205–27, 2009. https://doi.org/10.1016/S1877-1173(09)86007-9.
Martemyanov KA, Arshavsky VY. Biology and functions of the RGS9 isoforms. In 2009. p. 205–27.
Martemyanov, Kirill A., and Vadim Y. Arshavsky. Biology and functions of the RGS9 isoforms. Vol. 86, 2009, pp. 205–27. Pubmed, doi:10.1016/S1877-1173(09)86007-9.
Martemyanov KA, Arshavsky VY. Biology and functions of the RGS9 isoforms. 2009. p. 205–227.

DOI

Publication Date

2009

Volume

86

Start / End Page

205 / 227

Related Subject Headings

  • RGS Proteins
  • Protein Structure, Tertiary
  • Protein Isoforms
  • Protein Binding
  • Photoreceptor Cells, Vertebrate
  • Light Signal Transduction
  • Humans
  • Animals