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A patient with extensive stem cell factor-induced hyperpigmentation.

Publication ,  Journal Article
Bellet, JS; Obadiah, JM; Frothingham, BM; Kurtzberg, J; Grichnik, JM
Published in: Cutis
February 2003

Stem cell factor (SCF) is a cytokine that stimulates development of erythroid precursors and, consequently, may have potential importance in the treatment of certain anemias. We report a case of a young woman with Diamond-Blackfan anemia who received SCF treatment. One effect of SCF treatment is cutaneous hyperpigmentation at the injection site. In contrast to previously reported cases of patients who had fewer SCF injections, her hyperpigmentation was extensive and of major cosmetic concern. SCF may play a role in a number of disease processes. This case demonstrates the need to consider the potential pigmentary side effects of SCF therapy and to make careful selection of the injection sites.

Duke Scholars

Published In

Cutis

ISSN

0011-4162

Publication Date

February 2003

Volume

71

Issue

2

Start / End Page

149 / 152

Location

United States

Related Subject Headings

  • Stem Cell Factor
  • Injections, Subcutaneous
  • Hyperpigmentation
  • Humans
  • Female
  • Dermatology & Venereal Diseases
  • Anemia, Diamond-Blackfan
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bellet, J. S., Obadiah, J. M., Frothingham, B. M., Kurtzberg, J., & Grichnik, J. M. (2003). A patient with extensive stem cell factor-induced hyperpigmentation. Cutis, 71(2), 149–152.
Bellet, Jane S., Joseph M. Obadiah, Barbara M. Frothingham, Joanne Kurtzberg, and James M. Grichnik. “A patient with extensive stem cell factor-induced hyperpigmentation.Cutis 71, no. 2 (February 2003): 149–52.
Bellet JS, Obadiah JM, Frothingham BM, Kurtzberg J, Grichnik JM. A patient with extensive stem cell factor-induced hyperpigmentation. Cutis. 2003 Feb;71(2):149–52.
Bellet, Jane S., et al. “A patient with extensive stem cell factor-induced hyperpigmentation.Cutis, vol. 71, no. 2, Feb. 2003, pp. 149–52.
Bellet JS, Obadiah JM, Frothingham BM, Kurtzberg J, Grichnik JM. A patient with extensive stem cell factor-induced hyperpigmentation. Cutis. 2003 Feb;71(2):149–152.

Published In

Cutis

ISSN

0011-4162

Publication Date

February 2003

Volume

71

Issue

2

Start / End Page

149 / 152

Location

United States

Related Subject Headings

  • Stem Cell Factor
  • Injections, Subcutaneous
  • Hyperpigmentation
  • Humans
  • Female
  • Dermatology & Venereal Diseases
  • Anemia, Diamond-Blackfan
  • Adult