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Management Options in Advanced Prostate Cancer: What is the Role for Sipuleucel-T?

Publication ,  Journal Article
Bitting, RL; Armstrong, AJ; George, DJ
Published in: Clin Med Insights Oncol
2011

Most prostate cancer-related deaths occur in patients with castration-resistant prostate cancer (CRPC). Until recently, only therapy with docetaxel and prednisone has been shown to prolong survival in men with metastatic CRPC. With the United States Food and Drug Administration (US FDA) approvals of sipuleucel-T, cabazitaxel, and abiraterone acetate, all based on improvement in overall survival, the landscape for management of men with metastatic CRPC has dramatically changed. In this review we will discuss the pivotal clinical trial data leading to these approvals, with particular focus on the unique indication for sipuleucel-T and the implications for optimal management and sequencing of treatment in this patient population.

Duke Scholars

Published In

Clin Med Insights Oncol

DOI

EISSN

1179-5549

Publication Date

2011

Volume

5

Start / End Page

325 / 332

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bitting, R. L., Armstrong, A. J., & George, D. J. (2011). Management Options in Advanced Prostate Cancer: What is the Role for Sipuleucel-T? Clin Med Insights Oncol, 5, 325–332. https://doi.org/10.4137/CMO.S5977
Bitting, Rhonda L., Andrew J. Armstrong, and Daniel J. George. “Management Options in Advanced Prostate Cancer: What is the Role for Sipuleucel-T?Clin Med Insights Oncol 5 (2011): 325–32. https://doi.org/10.4137/CMO.S5977.
Bitting RL, Armstrong AJ, George DJ. Management Options in Advanced Prostate Cancer: What is the Role for Sipuleucel-T? Clin Med Insights Oncol. 2011;5:325–32.
Bitting, Rhonda L., et al. “Management Options in Advanced Prostate Cancer: What is the Role for Sipuleucel-T?Clin Med Insights Oncol, vol. 5, 2011, pp. 325–32. Pubmed, doi:10.4137/CMO.S5977.
Bitting RL, Armstrong AJ, George DJ. Management Options in Advanced Prostate Cancer: What is the Role for Sipuleucel-T? Clin Med Insights Oncol. 2011;5:325–332.

Published In

Clin Med Insights Oncol

DOI

EISSN

1179-5549

Publication Date

2011

Volume

5

Start / End Page

325 / 332

Location

United States