Do urodynamic parameters predict persistent postoperative stress incontinence after midurethral sling? A systematic review.

INTRODUCTION AND HYPOTHESIS: It is unclear whether preoperative urodynamic study (UDS) values are predictive of outcomes after midurethral sling. MATERIALS AND METHODS: We systematically reviewed multiple databases from January 1989 to October 2011 for English-language studies correlating UDS data with postoperative outcomes after midurethral slings. We performed random effects model meta-analyses, as indicated. Relative risk (RR) ratios for the outcome of stress urinary incontinence (SUI) cure were calculated using high maximum urethral closure pressure (MUCP) and Valsalva leak point pressure (VLPP) values as the reference group. RESULTS: High preoperative MUCP was associated with cure after retropubic [RR 0.67; 95% confidence interval (CI) 0.47-0.97)] and transobturator slings (RR 0.65; 95% CI 0.49-0.90). High preoperative VLPP was also associated with cure after retropubic sling (RR 0.89; 95% CI 0.82-0.96), but this relationship did not achieve statistical significance for cure after transobturator sling (RR 0.86; 95% CI 0.74-1.00). CONCLUSIONS: Preoperative MUCP and VLPP values may add insight into postoperative outcomes after surgical treatment for SUI.

Duke Scholars

Author Alison Catherine Weidner Obstetrics and Gynecology, Urogynecology

Author Amie Kawasaki Obstetrics and Gynecology, Urogynecology

Author Cindy Louise Amundsen Obstetrics and Gynecology, Urogynecology

Author Nazema Yusuf Siddiqui Obstetrics and Gynecology, Urogynecology