Skip to main content
Journal cover image

Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study).

Publication ,  Journal Article
Kandzari, DE; Chu, A; Brodie, BR; Stuckey, TA; Hermiller, JB; Vetrovec, GW; Hannan, KL; Krucoff, MW; Christenson, RH; Gibbons, RJ; Sigmon, KN ...
Published in: Am J Cardiol
March 1, 2004

In a nonrandomized feasibility study of therapeutic hypothermia in acute myocardial infarction, 18 patients were treated with endovascular cooling (Alsius, Irvine, California) as adjunctive therapy to primary percutaneous coronary intervention to assess measures of infarct size (area under the curve creatinine kinase-MB and technetium-99m single-photon emission computed tomography sestamibi) and the quality of myocardial perfusion (continuous ST-segment monitoring). Periprocedural endovascular cooling successfully decreased core body temperature (median 33.5 degrees C) and was well tolerated, which supports the evaluation of adjunctive hypothermia in pivotal trials to limit infarct size and decrease reperfusion injury.

Duke Scholars

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

March 1, 2004

Volume

93

Issue

5

Start / End Page

636 / 639

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Tomography, Emission-Computed, Single-Photon
  • Pilot Projects
  • Myocardial Reperfusion Injury
  • Myocardial Infarction
  • Middle Aged
  • Male
  • Isoenzymes
  • Hypothermia, Induced
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kandzari, D. E., Chu, A., Brodie, B. R., Stuckey, T. A., Hermiller, J. B., Vetrovec, G. W., … Califf, R. M. (2004). Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study). Am J Cardiol, 93(5), 636–639. https://doi.org/10.1016/j.amjcard.2003.11.038
Kandzari, David E., Alan Chu, Bruce R. Brodie, Thomas A. Stuckey, James B. Hermiller, George W. Vetrovec, Karen L. Hannan, et al. “Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study).Am J Cardiol 93, no. 5 (March 1, 2004): 636–39. https://doi.org/10.1016/j.amjcard.2003.11.038.
Kandzari DE, Chu A, Brodie BR, Stuckey TA, Hermiller JB, Vetrovec GW, et al. Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study). Am J Cardiol. 2004 Mar 1;93(5):636–9.
Kandzari, David E., et al. “Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study).Am J Cardiol, vol. 93, no. 5, Mar. 2004, pp. 636–39. Pubmed, doi:10.1016/j.amjcard.2003.11.038.
Kandzari DE, Chu A, Brodie BR, Stuckey TA, Hermiller JB, Vetrovec GW, Hannan KL, Krucoff MW, Christenson RH, Gibbons RJ, Sigmon KN, Garg J, Hasselblad V, Collins K, Harrington RA, Berger PB, Chronos NA, Hochman JS, Califf RM. Feasibility of endovascular cooling as an adjunct to primary percutaneous coronary intervention (results of the LOWTEMP pilot study). Am J Cardiol. 2004 Mar 1;93(5):636–639.
Journal cover image

Published In

Am J Cardiol

DOI

ISSN

0002-9149

Publication Date

March 1, 2004

Volume

93

Issue

5

Start / End Page

636 / 639

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Tomography, Emission-Computed, Single-Photon
  • Pilot Projects
  • Myocardial Reperfusion Injury
  • Myocardial Infarction
  • Middle Aged
  • Male
  • Isoenzymes
  • Hypothermia, Induced
  • Humans