Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel

An automated intensity-weighted brachytherapy seed localization algorithm.

Publication ,  Journal Article
Whitehead, G; Chang, Z; Ji, J
Published in: Med Phys
March 2008

Brachytherapy has proven to be an effective treatment for various forms of cancer, whereby radioactive material is inserted directly into the body to maximize dosage to malignant tumors while preserving healthy tissue. In order to validate the preoperative or intraoperative dosimetric model, a postimplant evaluation procedure is needed to ensure that the locations of the implanted seeds are consistent with the planning stage. Moreover, development of an automated algorithm for seed detection and localization is necessary to expedite the postimplant evaluation process and reduce human error. Most previously reported algorithms have performed binary transforms on images before attempting to localize seeds. Furthermore, traditional approaches based upon three-dimensional seed shape parameterization and matching require high resolution imaging. The authors propose a new computationally efficient algorithm for automatic seed localization for full three-dimensional, low-resolution data sets that directly applies voxel intensity to the estimation of both seed centroid location and angular seed orientation. Computer simulations, phantom studies, and in vivo computed tomography prostate seed imaging results show that the proposed algorithm can produce reliable results even for low-resolution images.

Duke Scholars

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

March 2008

Volume

35

Issue

3

Start / End Page

818 / 827

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Prostate
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Models, Statistical
  • Male
  • Humans
  • Brachytherapy
  • Automation
  • Algorithms
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Whitehead, G., Chang, Z., & Ji, J. (2008). An automated intensity-weighted brachytherapy seed localization algorithm. Med Phys, 35(3), 818–827. https://doi.org/10.1118/1.2836418
Whitehead, Gregory, Zheng Chang, and Jim Ji. “An automated intensity-weighted brachytherapy seed localization algorithm.Med Phys 35, no. 3 (March 2008): 818–27. https://doi.org/10.1118/1.2836418.
Whitehead G, Chang Z, Ji J. An automated intensity-weighted brachytherapy seed localization algorithm. Med Phys. 2008 Mar;35(3):818–27.
Whitehead, Gregory, et al. “An automated intensity-weighted brachytherapy seed localization algorithm.Med Phys, vol. 35, no. 3, Mar. 2008, pp. 818–27. Pubmed, doi:10.1118/1.2836418.
Whitehead G, Chang Z, Ji J. An automated intensity-weighted brachytherapy seed localization algorithm. Med Phys. 2008 Mar;35(3):818–827.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

March 2008

Volume

35

Issue

3

Start / End Page

818 / 827

Location

United States

Related Subject Headings

  • Tomography, X-Ray Computed
  • Prostate
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Models, Statistical
  • Male
  • Humans
  • Brachytherapy
  • Automation
  • Algorithms