Effect of hypophysectomy on somatostatin-14 and somatostatin-28 biosynthesis in the rat hypothalamus.
Publication
, Journal Article
Wetsel, WC; Fernstrom, JD
Published in: Brain Res
April 9, 1986
The in vivo incorporation of [35S]cysteine into hypothalamic somatostatin-28 was found to be substantially below normal in hypophysectomized rats. A smaller reduction in label incorporation into arginine vasopressin was also observed, while incorporation into acid-precipitable protein was normal. The diminution in somatostatin biosynthesis presumably reflects the absence of pituitary growth hormone secretion, while that in vasopressin synthesis may reflect the loss or disruption of vasopressin-producing cells.
Duke Scholars
Published In
Brain Res
DOI
ISSN
0006-8993
Publication Date
April 9, 1986
Volume
370
Issue
2
Start / End Page
315 / 320
Location
Netherlands
Related Subject Headings
- Sulfur Radioisotopes
- Somatostatin-28
- Somatostatin
- Rats, Inbred Strains
- Rats
- Protein Precursors
- Neurology & Neurosurgery
- Nerve Tissue Proteins
- Male
- Kinetics
Citation
APA
Chicago
ICMJE
MLA
NLM
Wetsel, W. C., & Fernstrom, J. D. (1986). Effect of hypophysectomy on somatostatin-14 and somatostatin-28 biosynthesis in the rat hypothalamus. Brain Res, 370(2), 315–320. https://doi.org/10.1016/0006-8993(86)90486-5
Wetsel, W. C., and J. D. Fernstrom. “Effect of hypophysectomy on somatostatin-14 and somatostatin-28 biosynthesis in the rat hypothalamus.” Brain Res 370, no. 2 (April 9, 1986): 315–20. https://doi.org/10.1016/0006-8993(86)90486-5.
Wetsel WC, Fernstrom JD. Effect of hypophysectomy on somatostatin-14 and somatostatin-28 biosynthesis in the rat hypothalamus. Brain Res. 1986 Apr 9;370(2):315–20.
Wetsel, W. C., and J. D. Fernstrom. “Effect of hypophysectomy on somatostatin-14 and somatostatin-28 biosynthesis in the rat hypothalamus.” Brain Res, vol. 370, no. 2, Apr. 1986, pp. 315–20. Pubmed, doi:10.1016/0006-8993(86)90486-5.
Wetsel WC, Fernstrom JD. Effect of hypophysectomy on somatostatin-14 and somatostatin-28 biosynthesis in the rat hypothalamus. Brain Res. 1986 Apr 9;370(2):315–320.
Published In
Brain Res
DOI
ISSN
0006-8993
Publication Date
April 9, 1986
Volume
370
Issue
2
Start / End Page
315 / 320
Location
Netherlands
Related Subject Headings
- Sulfur Radioisotopes
- Somatostatin-28
- Somatostatin
- Rats, Inbred Strains
- Rats
- Protein Precursors
- Neurology & Neurosurgery
- Nerve Tissue Proteins
- Male
- Kinetics