Skip to main content

Management of acute decompensated heart failure.

Publication ,  Journal Article
Allen, LA; O'Connor, CM
Published in: CMAJ
March 13, 2007

Acute decompensated heart failure represents a heterogeneous group of disorders that typically present as dyspnea, edema and fatigue. Despite the high prevalence of this condition and its associated major morbidity and mortality, diagnosis can be difficult, and optimal treatment remains poorly defined. Identification of the acute triggers for the decompensation as well as noninvasive characterization of cardiac filling pressures and output is central to management. Diuretics, vasodilators, continuous positive airway pressure and inotropes can be used to alleviate symptoms. However, few agents currently available for the treatment of acute decompensated heart failure have been definitively shown in large prospective randomized clinical trials to provide meaningful improvements in intermediate-term clinical outcomes. Multiple novel therapies are being developed, but previous treatment failures indicate that progress in the management of acute decompensated heart failure is likely to be slow.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

CMAJ

DOI

EISSN

1488-2329

Publication Date

March 13, 2007

Volume

176

Issue

6

Start / End Page

797 / 805

Location

Canada

Related Subject Headings

  • Vasodilator Agents
  • Ultrafiltration
  • Survival Analysis
  • Severity of Illness Index
  • Risk Assessment
  • Randomized Controlled Trials as Topic
  • Mineralocorticoid Receptor Antagonists
  • Middle Aged
  • Male
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Allen, L. A., & O’Connor, C. M. (2007). Management of acute decompensated heart failure. CMAJ, 176(6), 797–805. https://doi.org/10.1503/cmaj.051620
Allen, Larry A., and Christopher M. O’Connor. “Management of acute decompensated heart failure.CMAJ 176, no. 6 (March 13, 2007): 797–805. https://doi.org/10.1503/cmaj.051620.
Allen LA, O’Connor CM. Management of acute decompensated heart failure. CMAJ. 2007 Mar 13;176(6):797–805.
Allen, Larry A., and Christopher M. O’Connor. “Management of acute decompensated heart failure.CMAJ, vol. 176, no. 6, Mar. 2007, pp. 797–805. Pubmed, doi:10.1503/cmaj.051620.
Allen LA, O’Connor CM. Management of acute decompensated heart failure. CMAJ. 2007 Mar 13;176(6):797–805.

Published In

CMAJ

DOI

EISSN

1488-2329

Publication Date

March 13, 2007

Volume

176

Issue

6

Start / End Page

797 / 805

Location

Canada

Related Subject Headings

  • Vasodilator Agents
  • Ultrafiltration
  • Survival Analysis
  • Severity of Illness Index
  • Risk Assessment
  • Randomized Controlled Trials as Topic
  • Mineralocorticoid Receptor Antagonists
  • Middle Aged
  • Male
  • Humans