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Priority of the anti-idiotypic response after antigen administration: artefact or intriguing network mechanism?

Publication ,  Journal Article
Cerny, J; Kelsoe, G
Published in: Immunology Today
January 1, 1984

Immunization triggers at least two speck responses measurable at cellular and humoral levels: the antigen-driven proliferation of idiotype-bearing (idt+) cells; and an autochthonous anti-idt response'. As the expansion of the idt* clone(s) is presumed to provide the activating stimulus for the complementary response, one expects the proliferation of anti-idt clones to follow the idt response at an interval equivalent to the time required for ~pmphocyte activation. However, there have been several reports of an autochthonous anti-idt response preceding the expansion of antigen-driven idt' clone(s). In this brief commentary, we examine these reports and offer some suggestions that may resolve this apparent paradox. © 1984.

Duke Scholars

Published In

Immunology Today

DOI

ISSN

0167-5699

Publication Date

January 1, 1984

Volume

5

Issue

3

Start / End Page

61 / 63

Related Subject Headings

  • Immunology
  • 3204 Immunology
  • 3101 Biochemistry and cell biology
  • 1107 Immunology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cerny, J., & Kelsoe, G. (1984). Priority of the anti-idiotypic response after antigen administration: artefact or intriguing network mechanism? Immunology Today, 5(3), 61–63. https://doi.org/10.1016/0167-5699(84)90165-8
Cerny, J., and G. Kelsoe. “Priority of the anti-idiotypic response after antigen administration: artefact or intriguing network mechanism?Immunology Today 5, no. 3 (January 1, 1984): 61–63. https://doi.org/10.1016/0167-5699(84)90165-8.
Cerny, J., and G. Kelsoe. “Priority of the anti-idiotypic response after antigen administration: artefact or intriguing network mechanism?Immunology Today, vol. 5, no. 3, Jan. 1984, pp. 61–63. Scopus, doi:10.1016/0167-5699(84)90165-8.

Published In

Immunology Today

DOI

ISSN

0167-5699

Publication Date

January 1, 1984

Volume

5

Issue

3

Start / End Page

61 / 63

Related Subject Headings

  • Immunology
  • 3204 Immunology
  • 3101 Biochemistry and cell biology
  • 1107 Immunology