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Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation

Publication ,  Journal Article
Lyman, GH; Preisler, HD; Papahadjopoulos, D
Published in: Nature
1976

DMSO and other cryoprotective agents produce a pronounced increase on the phase transition temperature of phospholipid membranes, indicating an increased stability. The plateau phase of DMSO and the other cryoprotective agents, divalent cations, and local anesthetics on the transition temperature of phospholipid membranes seem to correlate with their effects on the differentiation of Friend leukemic cells in vitro. These studies suggest that the induction of differentiation by cryoprotective agents may be treatment result of the interaction of these agents with cell membranes.

Duke Scholars

Published In

Nature

Publication Date

1976

Volume

262

Issue

5567

Start / End Page

360 / 363

Related Subject Headings

  • General Science & Technology
 

Citation

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MLA
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Lyman, G. H., Preisler, H. D., & Papahadjopoulos, D. (1976). Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation. Nature, 262(5567), 360–363.
Lyman, G. H., H. D. Preisler, and D. Papahadjopoulos. “Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation.” Nature 262, no. 5567 (1976): 360–63.
Lyman GH, Preisler HD, Papahadjopoulos D. Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation. Nature. 1976;262(5567):360–3.
Lyman, G. H., et al. “Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation.” Nature, vol. 262, no. 5567, 1976, pp. 360–63.
Lyman GH, Preisler HD, Papahadjopoulos D. Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation. Nature. 1976;262(5567):360–363.

Published In

Nature

Publication Date

1976

Volume

262

Issue

5567

Start / End Page

360 / 363

Related Subject Headings

  • General Science & Technology