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Identification of genetic defect of an epilepsy: strategies for therapeutic advances.

Publication ,  Journal Article
McNamara, JO
Published in: Epilepsia
1994

Advances in molecular genetics and molecular biology are transforming the biology of human disease. Cures for diseases previously refractory to all treatments have become the reality for some disorders and the legitimate promise for others. In the case of the epilepsies, identification of mutant genes underlying familial epilepsies may lead to a new pharmacology, through the development of in vitro expression systems permitting rapid search for novel drugs, creation of highly specific animal models based on expression of the precise mutation, and correction of disease phenotype by introducing novel and highly specific genetic information into the person with epilepsy.

Duke Scholars

Published In

Epilepsia

DOI

ISSN

0013-9580

Publication Date

1994

Volume

35 Suppl 1

Start / End Page

S51 / S57

Location

United States

Related Subject Headings

  • Rabbits
  • Phenotype
  • Neurology & Neurosurgery
  • Mutation
  • Molecular Biology
  • Hypercholesterolemia
  • Humans
  • Genetic Therapy
  • Genetic Diseases, Inborn
  • Gene Expression
 

Citation

APA
Chicago
ICMJE
MLA
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McNamara, J. O. (1994). Identification of genetic defect of an epilepsy: strategies for therapeutic advances. Epilepsia, 35 Suppl 1, S51–S57. https://doi.org/10.1111/j.1528-1157.1994.tb05929.x
McNamara, J. O. “Identification of genetic defect of an epilepsy: strategies for therapeutic advances.Epilepsia 35 Suppl 1 (1994): S51–57. https://doi.org/10.1111/j.1528-1157.1994.tb05929.x.
McNamara, J. O. “Identification of genetic defect of an epilepsy: strategies for therapeutic advances.Epilepsia, vol. 35 Suppl 1, 1994, pp. S51–57. Pubmed, doi:10.1111/j.1528-1157.1994.tb05929.x.
Journal cover image

Published In

Epilepsia

DOI

ISSN

0013-9580

Publication Date

1994

Volume

35 Suppl 1

Start / End Page

S51 / S57

Location

United States

Related Subject Headings

  • Rabbits
  • Phenotype
  • Neurology & Neurosurgery
  • Mutation
  • Molecular Biology
  • Hypercholesterolemia
  • Humans
  • Genetic Therapy
  • Genetic Diseases, Inborn
  • Gene Expression