
Identification of genetic defect of an epilepsy: strategies for therapeutic advances.
Publication
, Journal Article
McNamara, JO
Published in: Epilepsia
1994
Advances in molecular genetics and molecular biology are transforming the biology of human disease. Cures for diseases previously refractory to all treatments have become the reality for some disorders and the legitimate promise for others. In the case of the epilepsies, identification of mutant genes underlying familial epilepsies may lead to a new pharmacology, through the development of in vitro expression systems permitting rapid search for novel drugs, creation of highly specific animal models based on expression of the precise mutation, and correction of disease phenotype by introducing novel and highly specific genetic information into the person with epilepsy.
Duke Scholars
Published In
Epilepsia
DOI
ISSN
0013-9580
Publication Date
1994
Volume
35 Suppl 1
Start / End Page
S51 / S57
Location
United States
Related Subject Headings
- Rabbits
- Phenotype
- Neurology & Neurosurgery
- Mutation
- Molecular Biology
- Hypercholesterolemia
- Humans
- Genetic Therapy
- Genetic Diseases, Inborn
- Gene Expression
Citation
APA
Chicago
ICMJE
MLA
NLM
McNamara, J. O. (1994). Identification of genetic defect of an epilepsy: strategies for therapeutic advances. Epilepsia, 35 Suppl 1, S51–S57. https://doi.org/10.1111/j.1528-1157.1994.tb05929.x
McNamara, J. O. “Identification of genetic defect of an epilepsy: strategies for therapeutic advances.” Epilepsia 35 Suppl 1 (1994): S51–57. https://doi.org/10.1111/j.1528-1157.1994.tb05929.x.
McNamara JO. Identification of genetic defect of an epilepsy: strategies for therapeutic advances. Epilepsia. 1994;35 Suppl 1:S51–7.
McNamara, J. O. “Identification of genetic defect of an epilepsy: strategies for therapeutic advances.” Epilepsia, vol. 35 Suppl 1, 1994, pp. S51–57. Pubmed, doi:10.1111/j.1528-1157.1994.tb05929.x.
McNamara JO. Identification of genetic defect of an epilepsy: strategies for therapeutic advances. Epilepsia. 1994;35 Suppl 1:S51–S57.

Published In
Epilepsia
DOI
ISSN
0013-9580
Publication Date
1994
Volume
35 Suppl 1
Start / End Page
S51 / S57
Location
United States
Related Subject Headings
- Rabbits
- Phenotype
- Neurology & Neurosurgery
- Mutation
- Molecular Biology
- Hypercholesterolemia
- Humans
- Genetic Therapy
- Genetic Diseases, Inborn
- Gene Expression