Evaluation of in vitro antifungal activity of LY121019.
Publication
, Journal Article
Hobbs, M; Perfect, J; Durack, D
Published in: Eur J Clin Microbiol Infect Dis
February 1988
LY121019 is a new semisynthetic lipopeptide antifungal agent with potent in vitro fungicidal activity against multiple clinical strains of Candida albicans and Candida tropicalis but is 10-100 fold less active against Torulopsis glabrata and Candida parapsilosis. Its in vitro activity against Candida albicans and Candida tropicalis is comparable to that of amphotericin B. The in vitro fungicidal activity of this new agent supports further investigations into its use in treatment of Candida infections.
Duke Scholars
Published In
Eur J Clin Microbiol Infect Dis
DOI
ISSN
0934-9723
Publication Date
February 1988
Volume
7
Issue
1
Start / End Page
77 / 80
Location
Germany
Related Subject Headings
- Peptides, Cyclic
- Peptides
- Microbiology
- Humans
- Echinocandins
- Candida albicans
- Candida
- Antifungal Agents
- Amphotericin B
- 3207 Medical microbiology
Citation
APA
Chicago
ICMJE
MLA
NLM
Hobbs, M., Perfect, J., & Durack, D. (1988). Evaluation of in vitro antifungal activity of LY121019. Eur J Clin Microbiol Infect Dis, 7(1), 77–80. https://doi.org/10.1007/BF01962182
Hobbs, M., J. Perfect, and D. Durack. “Evaluation of in vitro antifungal activity of LY121019.” Eur J Clin Microbiol Infect Dis 7, no. 1 (February 1988): 77–80. https://doi.org/10.1007/BF01962182.
Hobbs M, Perfect J, Durack D. Evaluation of in vitro antifungal activity of LY121019. Eur J Clin Microbiol Infect Dis. 1988 Feb;7(1):77–80.
Hobbs, M., et al. “Evaluation of in vitro antifungal activity of LY121019.” Eur J Clin Microbiol Infect Dis, vol. 7, no. 1, Feb. 1988, pp. 77–80. Pubmed, doi:10.1007/BF01962182.
Hobbs M, Perfect J, Durack D. Evaluation of in vitro antifungal activity of LY121019. Eur J Clin Microbiol Infect Dis. 1988 Feb;7(1):77–80.
Published In
Eur J Clin Microbiol Infect Dis
DOI
ISSN
0934-9723
Publication Date
February 1988
Volume
7
Issue
1
Start / End Page
77 / 80
Location
Germany
Related Subject Headings
- Peptides, Cyclic
- Peptides
- Microbiology
- Humans
- Echinocandins
- Candida albicans
- Candida
- Antifungal Agents
- Amphotericin B
- 3207 Medical microbiology