
Alcoholism and depressive disorders: is cholinergic sensitivity a biological marker?
Publication
, Journal Article
Overstreet, DH; Janowsky, DS; Rezvani, AH
Published in: Alcohol Alcohol
1989
There is an overlap between alcoholism and depressive disorders. However, alcoholics tend to be resistant to the effect of cholinergic agonists, whereas depressives tend to be more sensitive. A recently developed animal model of depression which is more sensitive to cholinergic agonists is also more sensitive to the acute effects of ethanol. These consistent human and animal studies suggest that cholinergic challenges may be helpful in separating alcoholics from depressives.
Duke Scholars
Published In
Alcohol Alcohol
ISSN
0735-0414
Publication Date
1989
Volume
24
Issue
3
Start / End Page
253 / 255
Location
England
Related Subject Headings
- Substance Abuse
- Sleep, REM
- Receptors, Cholinergic
- Reaction Time
- Physostigmine
- Humans
- Evoked Potentials, Auditory
- Depressive Disorder
- Cholinergic Fibers
- Brain
Citation
APA
Chicago
ICMJE
MLA
NLM
Overstreet, D. H., Janowsky, D. S., & Rezvani, A. H. (1989). Alcoholism and depressive disorders: is cholinergic sensitivity a biological marker? Alcohol Alcohol, 24(3), 253–255.
Overstreet, D. H., D. S. Janowsky, and A. H. Rezvani. “Alcoholism and depressive disorders: is cholinergic sensitivity a biological marker?” Alcohol Alcohol 24, no. 3 (1989): 253–55.
Overstreet DH, Janowsky DS, Rezvani AH. Alcoholism and depressive disorders: is cholinergic sensitivity a biological marker? Alcohol Alcohol. 1989;24(3):253–5.
Overstreet, D. H., et al. “Alcoholism and depressive disorders: is cholinergic sensitivity a biological marker?” Alcohol Alcohol, vol. 24, no. 3, 1989, pp. 253–55.
Overstreet DH, Janowsky DS, Rezvani AH. Alcoholism and depressive disorders: is cholinergic sensitivity a biological marker? Alcohol Alcohol. 1989;24(3):253–255.

Published In
Alcohol Alcohol
ISSN
0735-0414
Publication Date
1989
Volume
24
Issue
3
Start / End Page
253 / 255
Location
England
Related Subject Headings
- Substance Abuse
- Sleep, REM
- Receptors, Cholinergic
- Reaction Time
- Physostigmine
- Humans
- Evoked Potentials, Auditory
- Depressive Disorder
- Cholinergic Fibers
- Brain